VEXAS (X-linked) Mutation in UBA1, the enzyme that initiates ubiquitylation. Most pts meet criteria for rheum (RP, Sweets, PAN, GCA) and heme (MDS, MM) diseases. Clinical: -Macrocytic anemia -Fever -Rash -🫁 infiltrates -🦻& 👁️ inflammation -VTE BMBx shows vacuolization.

Generally reach for MRA for treatment-resistant HTN in pts with eGFR ≥45 (Pathway-2 study), and for loop diuretic in pts with eGFR <45. But first, discuss lifestyle modifications and screen/treat secondary causes & OSA! ahajournals.org/doi/10.1161/CI… nejm.org/doi/full/10.10…

Alternate day dosing of PO iron supplementation may be preferable to consecutive day dosing. thelancet.com/journals/eclin…

Super excited to have presented our poster on pre-pregnancy cardiometabolic health and hypertensive disorders of pregnancy at #HopkinsResearchRetreat today. Thankful to Anum Minhas Allison G. Hays, MD

Vascular aging as identified by CT imaging can be utilized as a marker for aging phenotypes and aging trajectory 🔗atherosclerosis-journal.com/article/S0021-… Ellen Boakye, MD MPH Michael J. Blaha Khurram Nasir Josef Coresh Kuni Matsushita priyapalta Miguel Cainzos-Achirica Omar Dzaye Zeina Dardari Johns Hopkins Bloomberg School of Public Health

And He did it!!!

Cardiovascular Risk Profile Among Reproductive-Aged Women. Worsening suboptimal CVH largely explained by increase In obesity ⁦⁩⁩ ⁦Ellen Boakye, MD MPH⁩ ⁦Michael J. Blaha⁩ ⁦Khurram Nasir⁩ ⁦Sadiya Khan⁩ ⁦⁩ ⁦Michael Honigberg, MD, MPP⁩ ⁦ ajpmfocus.org/article/S2773-…

Excellent work by Ellen Boakye, MD MPH Head Coach/GM Garima Sharma M.D Johns Hopkins Ciccarone Center Johns Hopkins Cardiology Johns Hopkins Medicine Penn Cardiology #🥍🏏⚽️⛳️⚽️🎾

Older adults with CAC≥1000 have worse aging indices and aggregate aging scores European Atherosclerosis Society 🔗atherosclerosis-journal.com/article/S0021-… Ellen Boakye, MD MPH Michael J. Blaha Khurram Nasir Josef Coresh Kuni Matsushita priyapalta Miguel Cainzos-Achirica Omar Dzaye Zeina Dardari Johns Hopkins Bloomberg School of Public Health Miller Medicine

#ACC24 Chloe Duvall and I enjoyed presenting these posters from our team on insights from national vital statistics on prepregnancy cardiometabolic health. Anum Minhas Allison G. Hays, MD Erin D. Michos, M.D.

Perfect way to wrap up #ACC2024 Thanks for an incredible weekend #ACC

The 🔎 by Michael J. Blaha et al highlights #CAC as a simple measure associated w/ biological aging, w/ clinical and research implications for estimating the physical and physiological aging trajectory of older individuals 🔗atherosclerosis-journal.com/article/S0021-… Ellen Boakye, MD MPH Khurram Nasir

Grad pics today, can’t believe residency is nearly over! Looking forward to chief year with this crew 😍 Edan Zitelny Nichole Smith, MD Maggie Rowe

Check out our recent publication on AVC showing a stepwise increased risk of incident dementia even after adjusting for atherosclerotic risk factors and CAC scores. atherosclerosis-journal.com/article/S0021-… Jelani K. Grant Roger Blumenthal Seamus Whelton Johns Hopkins Ciccarone Center Alexander C. Razavi

Lp(a)❓LDL-C ❓AVC ❓How does their prognostic role in predicting incident aortic stenosis differ 🤔 Read our latest Circulation publication to find out ✅ Seamus Whelton Alexander C. Razavi Roger Blumenthal ahajournals.org/doi/10.1161/CI…

Olympic Gold Medalist Sydney McLaughlin on her relationship with God: “I credit all that I do to God. Regardless of what happens, He’s going to get the praise. Every time I step on the track I pray “let me be the vessel in which you’re glorified”… That’s why I do what I do.” 🙏

STEPH CURRY WITH THE SHOT OVER WEMBY 👨‍🍳

B cepacia Endocarditis in a Patient With Severe MAC sciencedirect.com/science/articl…

Proof of life. Alive and thriving 🍀