Our collaborative work with the ReGArDS team LBMC_Lyon on translation-dependent mRNA degradation upon anti-cancer MAPKi treatment is now online: academic.oup.com/narcancer/arti… #NAR_Cancer #Translation #Codon_usage #MAPKi

I am delighted to share the newest work from the Sternberg Lab, in which we discover RNA-templated gene creation as a mechanism of antiviral immunity. This is a story for anyone who loves molecular biology, and one that repeatedly left us in disbelief. doi.org/10.1101/2024.0…

New preprint from the lab ! This is a long-term collaboration with my colleague Gaël Yvert LBMC_Lyon on the kinetic characterization of an optogenetic tool his group developed to control Cre-mediated recombination in vivo. Experiments + modeling. biorxiv.org/content/10.110…

📢 Join us for the 7th Webinar for Early Career Investigators on "Ribosome Biogenesis and Regulation" 🗓️ Date: Tuesday, May 28th 🕒 Time: 14:00 PM CET Don't miss out on insights into ribosome rRNA heterogeneity! translacore.eu/event/6th-webi…

We are incredibly excited to have our first LncRNA screening paper published today in pnas . This project has been a labor of love for over 8years!! LncRNAs are tricky to tease apart mechanistically! Here we provide a resource of LncRNAs involved in macrophage differentiation

Join me today at poster 525 in the The RNA Society meeting #RNA24 to discuss 1) how the lncRNA TERRA could activate recombination of telomeres, and 2) the beautiful views from Arthur's Seat!

Un poste d'Ingénieur d'études biologiste en traitement des données (IE bioinformatique) est ouvert au concours au CNRS pour rejoindre notre unité ARN - IBMC - CNRS, merci de RT. CNRS Biologie tinyurl.com/yxv3sy5k

Ribosomes unexpectedly moonlight as activators of angiogenin enzyme nature.com/articles/d4158…

We are excited to introduce a new gRNA design tool for CRISPR based screening. This is the work of graduate student Eric Malekos. Can be used for multiple CRISPR systems, model organisms, targeting sORFs, noncoding regions and with allele specificity.

We are excited to present our work to identify new lncRNAs involved in mono-mac differentiation. This is the work of Christy 🧬 with help from other Carpenter lab members past and present. Christy presents two approaches to find functional lncRNAs.

Congratulations Daniel Jost and the team!

Our freshly opened team is looking for an enthusiastic engineer to identify Hox protein-RNA networks in Drosophila embryos at IGMM-Montpellier If you are interested, apply on CNRS portal: emploi.cnrs.fr/Offres/CDD/UMR… Please retweet! #jobOffer #RNA #hox #Drosophila

Delighted to share our new pre-print on translational activity of 80S monosomes. Albert Blandy Elton Vasconcelos Amy Turner, Ph.D FontanaLab Dr Michaela Agapiou Thanks to Biotechnology and Biological Sciences Research and Wellcome. Great for this work to benefit from RiboCode team input biorxiv.org/content/10.110…

Last chance to register and submit an abstract: abstract submission deadline extended until July 15. WE hope to see you all in Lisbon!

#SAMD9L is an antiviral factor against #HIV & primate lentiviruses, inhibiting viral & cell translation Thrilled our findings led by Alexandre Legrand found such a great home PLOS Biology ! CIRI Lyon CNRS Biologie Inserm ENS de Lyon Université de Lyon journals.plos.org/plosbiology/ar… (1/3)

Please RT: Are you a highly skilled, top-motivated biochemist looking for an exciting postdoc project? We are looking for you. For details, check here: ohws.prospective.ch/public/v1/jobs…

Preprint Gatfield lab,The Ban Lab& Teleman Lab w/ 1st author Romane Meurs "An in vitro assay of MCTS1-DENR-dependent re-initiation & ribosome profiling uncover the activity of MCTS2 and distinct function of eIF2D" bit.ly/4bPA9mg Adrian Bothe Center for Integrative Genomics, UNIL (CH) Université de Lausanne ETH Zurich DKFZ

A bit of advertising for our review. Please take a look - we definitely spent a lot of time on this and dipped our toes well outside our comfort zone! Orchestrated centers for the production of proteins or “translation factories” - WIREs RNA wires.onlinelibrary.wiley.com/doi/10.1002/wr…

Beautiful work from the Doudna Lab to minimize as much as possible VLP assembly and maximise CRISPR-CAS9 RNP cargo loading for its delivery into target cells! Mechanism-guided engineering of a minimal biological particle for genome editing biorxiv.org/content/10.110…

Archaeovirology in the lab sequencing of Polioviruses stored for more than 60 years in a sealed box unlocked some mysteries DOI: 10.1093/ve/veae063