Why many Aβ-positive cognitively unimpaired individuals do not develop downstream tau pathology? Our new study led by Bruna Bellaver published in Nature Medicine shows that looking at reactive astrocytes may help start solving this question. rb.gy/y9qkj

Very interesting study by Bruna Bellaver, Tharick Pascoal et al.! Find the excellent Alzforum coverage (including Emma Coomans and my comment + several others) 👇

🚨🚨 have you filled out this survey yet? Are you going to #AAIC23? Please help by completing the survey below on the utility of tau-PET in clinical practice and in trials, results will be presented during the opening plenary session by RikOssenkoppele!

Several key findings here!! - A new way to quantify tau-PET abnormality based on spatial extent rather than SUVR load - Homogeneous spatial extent pattern in Braak's large ROI - Heterogeneous spatial extent patterns when targeting small ROI - faster tau propagation in MCI

Amazing plenary on tau-PET imaging at #AAIC23 by RikOssenkoppele!! Tau-PET is definitely here to stay! 🧠

In an excellent session on the role of vascular risk factors/pathology featuring among others Tessa Harrison, Prashanthi Vemuri and Luigi Lorenzini, Emma Coomans showed how amyloid load * vascular pathology impacted tau accumulation. #AAIC23 Alzheimercentrum Amsterdam BioFINDER

#AAIC23 has come to an end! It was so much fun having everyone in Amsterdam, looking forward to next year! Alzheimercentrum Amsterdam

Our new paper sheds light on the pathophysiogical and clinical trajectories of individuals presenting with confined MTL tau and no apparent amyloid pathology. Our data suggests that they are likely to follow a distinct, less malign course untypical for AD. Check it out JAMA Neurology

Interesse in een update over zorg en onderzoek rondom dementie? Meld je aan voor Alzheimer Actueel waar onder andere Suzan van Amerongen, Elliz Scheijbelaar en ik iets zullen vertellen over ons onderzoek 🧠 #WereldAlzheimerDag #Alzheimer10daagse

Interested in the complex interplay between cerebrovascular burden and Alzheimer’s disease pathology? 🧠 Check out our newest paper just published in Brain! Big thanks to all co-authors but especially Oskar Hansson and RikOssenkoppele!!

Happy that the final paper of my phd thesis is now out! If you are interested in tau-PET visual reads / the clinical implementation of tau-PET, check out our latest paper published in Neurology Neurology Journal Alzheimercentrum Amsterdam

Very interesting editorial: "The lack of adoption of (new) MRI biomarkers (in clinic) is a significant failure for the field of dementia imaging research, and it is unlikely that simply applying ever more sophisticated methods of machine learning [..] will change this situation."

Published online: Performance of a [18F]Flortaucipir PET Visual Read Method Across the Alzheimer Disease Continuum and in Dementia With Lewy Bodies bit.ly/45aRFOv #NeuroTwitter Emma Coomans RikOssenkoppele

What an excellent PhD defense of an extraordinary thesis yesterday! Proud and pleased that Emma Coomans will continue as a postdoctoral researcher on my European Research Council (ERC) project TAU-NOW. Alzheimercentrum Amsterdam

We are looking for a highly motivated #postdoc to join our team for an exciting collaborative project on #AI image analysis. The position entails working closely with academic and industry partners in Sweden, the US, the UK and Germany. Please share! web103.reachmee.com/ext/I005/1035/…

Yesterday was such a fun and beautiful day, racing through the Dutch countryside and raising money for Alzheimer’s research together with Michael Schöll and his beautiful car! Many thanks to the #AlzheimerRally2024 organization team for this great day! 🚗🚗

Writing this scientific commentary together with RikOssenkoppele was so much fun! Congrats to the authors for their paper recently published in Brain!

🔥Years in the making, now published! My final postdoc project in Nature Communications shows that Tau and TSPO PET follow gradients🌈 of connectivity in #Alzheimer disease 🧠 nature.com/articles/s4146… Thanks to Alzheimer's Association Sunnybrook Health Sciences Centre McGill Research Centre for Studies in Aging Now ready for new adventures!🌍☺️

🚨 NEW PREPRINT! "Prediction of future cognitive decline among cognitively unimpaired individuals using measures of soluble phosphorylated tau or tau tangle pathology" I am very pleased to present our most recent work! It concerns a large multi-cohort study in which we

After a few days in NY, my poster has reached its final destination! Stop by my poster today during AIC (nr. 64) and join our tau-PET-session during #AAIC24 on July 30th to hear about prevalence of tau-PET-positivity in a multicenter study including 41 (!) cohorts worldwide 🌎