ALL CHANGE - Treatment 165 (phesgo)/ 14 (kadcyla)/ 1 (first cycle Enhertu)

My recent update with fundraiser that steroids sorted my pressure/headaches worried me.

Flew home Sunday 21st from Spain. Monday onc rang re additional PETCT scan to the issues he shared with me before…

Comprehensive mutational scanning of #EGFR reveals TKI sensitivities of extracellular domain mutants. shorturl.at/lrI45

🧬Multiple EGFR extracellular domain variants, not associated with approved targeted therapies, were sensitive to afatinib and dacomitinib in vitro.…

New & available #OpenAccess | Impact of HIV status on prognosis of malignancies among people living with HIV in Japan

acsjournals.onlinelibrary.wiley.com/doi/10.1002/cn…

OncoAlert

Pembro&Nivo the new cappucino -only in the morning!!
ESMO - Eur. Oncology Annals of Oncology OncoAlert Dario Trapani Paolo Tarantino Ferraboschi

esmoopen.com/article/S2059-…

The NADINA trial of neoadjuvant ipi/nivo vs adjuvant nivo in melanoma is a plenary #ASCO24 . Shorter periods of therapy in responders (neoadjuvant alone) is an important question. Neoadjuvant nivo didn’t work in RCC (PROSPER). PACIFIC2 struggled in lung ascopubs.org/doi/10.1200/JC…

Congratulations Hope Rugo !!! This is VERY well deserved! Thank you for all your contributions to breast oncology!

OncoAlert #bcsm

Happening now!! ESMO - Eur. Oncology Virtual Plenary presenting the results of the randomized phase 3 study on Fuzuloparib +/- apatinib in HER2- metastatic #breastcancer patients with gBRCA1/2 mut
OncoAlert

Now presented at ESMO - Eur. Oncology Virtual Plenary: Fuzuloparib +/- apatinib⬆️ PFS compared to standard CT in HER2-neg metastatic #breastcancer patients with gBRCA1/2 mut
Median PFS 11 mos (F+A), 6.7 mos (F), 3.0 mos (CT)
No significant benefit in OS (but crossover was allowed)
OncoAlert

Make sure to mark your calendars for our upcoming tumor board webinar on June 27th at 18.00 CET.

Join us for a discussion led by various specialists on the topic of locally advanced cervical cancer.

Don't miss out on this informative event!

#ESGO #gynonc #surgeon #Oncoalert

Thanks IASLC ILNC for the opportunity to discuss this important topic with VCDenninghoff

The Tisch Cancer Institute OncoAlert International Society of Liquid Biopsy

Top advances of the year: Perioperative therapy for lung cancer 🫁 acsjournals.onlinelibrary.wiley.com/doi/10.1002/cn…

2023 saw multiple positive trials of ICIs incorporated into novel treatment paradigms for early stage NSCLC, including overall survival improvement.

@oncoalert Jackie Aredo Heather Wakelee

Evandro de Azambuja, MD, PhD discusses the results presented at ESMO - Eur. Oncology Virtual Plenary:
- improvement in PFS but also⬆️in toxicity;
- relatively small sample-size;
- Asian pts only (but no PARPi available in🇨🇳yet);
- results consistent according to HR status and prior platinum;
OncoAlert

This new editorial, which comments on the recent study by Dr. Sheri Spunt (Stanford Children's) et al, provides a comprehensive summary of 2 clinical trials on undifferentiated embryonal sarcoma of the liver from the major sarcoma groups. OncoAlert acsjournals.onlinelibrary.wiley.com/doi/10.1002/cn…

Out in Science Magazine

Finding the missing link between☀️ and🦀

☑️Vit-D availability >⬆️ Immune activation and IO efficacy

☑️Regulation of GI microbiome by Vit-D availability>Role of B. fragilis 🦠🦠

🔎Paves the way for more IO and Vit-D studies (PROVIDENCE study)

Congrats…

Effect of immunotherapy-infusion time of day on survival of patients with advanced cancers
Annals of Oncology
doi.org/10.1016/j.esmo…
🔎13 trials meta-analysis, 1663 pts
⚡️early ToD groups had longer OS (HR 0.50) & PFS (HR
0.51)
🧐Strong evidence for early ToD ICI infusions

Livestream is happening now!
Policy: The Future of Cancer Care  thehill.com/events/4582615… Oncology Nursing Society OncoAlert

Join us for our Post-ASCO 2024 Highlights 📣🩸

Featuring presentations & panel discussions on selected abstracts from #ASCO 2024 🔦

Agendas available soon 📝

REGISTER 👉 vjoncology.com/feature/post-a…

#ASCO 24 Sanjay Popat Tom Powles Sara Tolaney Lizzy Smyth

Out by our partner journal ACS Journal Cancer American Cancer Society 🇺🇸

OncoFertility🤰🏾
population-based study reveals that non-Hispanic Black adolescents and young adults (AYAs) with cancer are:

➡️ less likely to have live births after cancer compared to other racial/ethnic groups…

Read our May/June issue! 📕

acsjournals.onlinelibrary.wiley.com/toc/15424863/2…

In this issue:
✔️ Global cancer statistics by American Cancer Society and IARC
✔️ Integrating #GenomicTest results in #CancerCare by Raffaella Casolino et al
✔️ #Opioid analgesics for #CancerPain by Abdel Shaheed et al

OncoAlert