Impactful study - Perhaps (HOPEFULLY) the final nail in the coffin as to why it is absurd to use the term GOOD CHOLESTROL - any clinician using that archaic term should lose their license

Nice to have my declaration re docs misleading folks about high HDL-C or even worse the TC/HDL-C ratio to be sustained by a top cardiologist/lipidologist.

Here is an incredible article about LDL-C exposure over time and so sad it is firewalled for $40. Anyone advising patients about apoB or LDL-C should get this from their hospital library. National Lipid Association European Atherosclerosis Society European Atherosclerosis Society European Society of Cardiology #cholesterol

Lipidaholics: Do not be ready to bury fenofibrate just yet pubmed.ncbi.nlm.nih.gov/39075919/ Also there are retinal benefits. National Lipid Association European Atherosclerosis Society European Society of Cardiology International Atherosclerosis Society (IAS) #fenofibrate

With respect to the authors, like so many guidelines these will have little use in the real world and will be ignored. I agree with Sergio Kaiser MD, PhD, FACC, FESC 🇧🇷🇮🇱🇷🇴🇺🇦 on the misclassification of risk categories. Likewise it is also absurd to still suggest using high dose statins which almost no clinicians

Lipidaholics: Continuing the tutorial on cholesterol homeostasis by looking at the individual steps of hepatocellular cholesterol homeostasis. As always, the issues are way more complicated than I depict here. Many will be surprised that cholesterol can move from the bile back

Lipidaholics. All interested in sane advice on nutrition and lipids should follow my longtime friend and the NLA’s nutritional guru Carol Kirkpatrick, PhD, MPH, RDN, CLS, FNLA

This is an incredible open access Primary Prevention advice - Just about the best I have seen. ApoB oriented, no specific TG goal - although they should be tested or for sure no HDL-C goal. None of the absolute high-intensity statin silliness for primary prevention

The call for Anitschkow Prize 2025 nominations is now open! This esteemed prize, presented annually by the EAS, honors outstanding researchers who have made significant contributions to the field of atherosclerosis and related metabolic disturbances. eas.to/Anitschkow2025…

Lipidaholics - Continuing with my tutorial on the individual steps of hepatocellular cholesterol homeostasis. As always, the issues are way more complicated than I depict here. The LDLR regulates apoB (and apoE) particle clearance - Decreased clearance of LDLs is #1 cause of

Today's #LipidXcellence comes to us from the Foundation of the NLA with their #TweetorialTuesday breaking down what your patients need to know about lipid testing and what resources are available to them! Share with your patients! #CholesterolMonth #LipidXcellence #KnowledgeIsPower

I think some are misusing my response tweet below. Yes cholesterol is needed by all cells (to a very small degree) but equally true is the fact that excess cellular cholesterol can be incredibly toxic as it crystallizes and kills cells (lipotoxic). Importantly tissue (cellular)

Hate to say it but- HAVE PREACHED THIS since ~ 2000 Thank goodness many Lipidaholics followed my lead

Lipidaholics - Continuing with the next step in my tutorial on the individual steps of hepatocellular cholesterol homeostasis. As always, the issues are way more complicated than I depict here. SR-B1 is a fascinating bidirectional membrane transporter that can both lipidate or

More solid trial data to further bury the cholesterol denialists. Hope they read the manuscript. The great CARDIA study - Prediction of Cumulative Exposure to Atherogenic Lipids During Early Adulthood - THE LDLc & NON-HDL-C LEVELS IN YOUNG THAT BEST PREDICT RISK ARE FAR

Sorry deniers - Here is the editorial (CAPS are mine) that refutes everything you believe - "We need to be identifying more effective strategies [HOW ABOUT APOB] for lipid screening and lowering in this segment of the population [YOUNG ADULTS], and reducing health inequity by

The final hours of waiting for our third LatAm webinar! Today at 18:00 CET, we will explore more about triglyceride-rich lipoproteins as contributors to residual risk. You still have a chance to join us. Register here: eas.to/LatAmWeb3Reg

Spent 7 yeas in clinical biomarker labs, so start with your inquires.

#FacultyForumFriday is here! Thomas Dayspring is with us to answer your questions throughout the day! Comment on this post with your question and tag Thomas Dayspring! #LipidXcellence

This will surprise most: LDL receptors which clear the apoB-cholesterol carrying lipoproteins from plasma can be upregulated and act very quickly. When hepatic (liver) pools of cholesterol are depleted by any intervention like diet or drugs, plasma cholesterol levels change