PhD position available: please apply if you are interested in joining our lab to work on exciting new types of archaeal histones. See the advertisement for details. universiteitleiden.nl/vacatures/2024…

(1/13) Exciting findings from our latest study, now published in Nucleic Acids Res as a breakthrough article! academic.oup.com/nar/advance-ar…

Excited to share my PhD work in the lab of Lars Velten Centre for Genomic Regulation (CRG). We screened the activity of synthetic enhancers throughout myeloid differentiation. Combinations of activating TFs frequently neutralized each other or gained repression twtr.to/wiWIZ (1/n)

Happy to share our manuscript that demonstrates the HP1 alpha monomer-dimer transition to open and compact chromatin. Thanks to all of our collaborators Harvey Lab Elizabeth Hinde Mark Dawson Rhys Allan Charlie Bell academic.oup.com/nar/advance-ar…

My favourite discovery ever has just come online. Can I please tell you about some seriously wacky molecular biology? The story starts with a reverse transcriptase that SOMEHOW defends bacteria from viruses. (👇 I recommend sound ON for the video 🎹) 1/

EHA Research Conference in Malaga In March 2025: "Transcriptional control and chromatin alterations in normal and malignant hematopoiesis" Fantastic opportunity for junior investigators to present and discuss their work with young and experienced scientists. Great program!

Interested in doing crazy/creative/high impact science at the intersection of ML/synthetic biology/gene regulation/genetics/personalized medicine? Due to a string of recent grant successes we have multiple postdoc openings... ubc.wd10.myworkdayjobs.com/en-US/ubcfacul… Thanks in advance for sharing!

Today in @natchembio we share a new strategy to design fully synthetic “artificial” bZIP family transcription factors that directly block DNA binding of HIF1a and XBP1 to inhibit hypoxia-dependent oncogenic signaling in cells and in vivo. 1/n  nature.com/articles/s4158…

We developed a simple highly-optimized version of 2nd gen Hi-C, called FLIE HI-C, which takes 2 days instead of 4-5, uses 5-20 fold less reagents, and needs only 100-1000 fold less input material. Importantly, we keep all the controls and the interaction map quality is excellent.

Hurry up! Last day to submit abstract for "Genomics in Ageing and Disease" (Colchester, 16th September). Free Registration! Talks by Peter Fraser, Aimée Parker, Gabi Ficz, Anton Enright, @R_Rahbari, Ozgen Deniz, Jordana Bell, Sarah Marzi & Essex PIs gate.essex.ac.uk

🎉 Excited to share the peer-reviewed version of our manuscript describing COBIND, a tool for revealing TF co-binding patterns using non-negative matrix factorization. Great work led by Ieva Rauluševičiūtė NCMM Nordic EMBL P'ship UiO - Det medisinske fakultet Universitetet i Oslo academic.oup.com/nar/advance-ar… Nucleic Acids Res

We will have an opening for a PhD position in that round! Students with computational and theoretical background are encouraged to apply! Cool gene regulation projects at the heard of EU science. Please DM me if you have Q.

The Fantastic PhD work of Annalise Zouein is out now!: Engineered Transcription Factor Binding Arrays for Expression Control in Mammalian Cells biorxiv.org/content/10.110… This would have not been possible without Tom Ellis! Grateful to Katie Galloway for working with us!

Do I know someone from the Universities of Southampton, Sussex, Kent, or Portsmouth, who work on liquid biopsies, cell-free DNA, or nucleosome positioning? Looking for a partner to develop a joint PhD project for the SoCoBio DTP, which the University of Essex is planning to join

Explore how #Epigenomics advances are accelerating research and driving innovative therapies for common human diseases. Join us for #Epigenomics25 to discover the latest breakthroughs supporting your research. 📅 12-14 March 2025 📎 bit.ly/3WRei9M #AcademicChatter

who has successfully done cut and tag on histone H4 pan or penta acetyl? i have questions

Nucleosome remodeler exclusion by histone deacetylation enforces heterochromatic silencing and epigenetic inheritance dlvr.it/TCsycz

🎉 Exciting Announcement! 🎉 “Histone Modifications and Chromatin Structure Symposium” 🗓️ Dates: October 17-18, 2024 📍 Location: National Institutes of Health, Bethesda, Maryland The NCI Center of Excellence in Chromosome Biology is delighted to invite you to our upcoming

Our single-cell, pan-cancer analysis of open chromatin in human cancers, done in collaboration with TCGA and the Chang and Corces labs (among others including Illumina), is out in Science today. Congrats to Laksshman Sundaram and all authors! science.org/doi/10.1126/sc…