Issue 27 is here 🎉 Our front cover this week features Ana Pizarro Sonia Infante-Tadeo et al. at IMDEA Nanociencia 🔬's latest article 😍 Osmium(ii) tethered half-sandwich complexes: pH-dependent aqueous speciation & transfer hydrogenation in cells 🔗 ow.ly/o6fq50FvP6j #ChemSciCovers🎨

Sonia Infante Tadeo, PhD student at IMDEA Nanociencia 🔬, will defend her thesis "Reversible Activation Dynamics of Tethered Osmium(II) Half-Sandwich Complexes for Biological Applications" - supervised by Ana Pizarro. 📆 Oct. 14th 2021, 12:00 📍 Conference room nanociencia.imdea.org/home-en/events…

I invite you to read my poster "Osmium(II) Tethered Half-Sandwich Complexes: pH-dependent Aqueous Speciation and Transfer Hydrogenation in Cells" to discover more about new osmium(II) arene #metallodrugs from Ana Pizarro group Glad to share it at the 11th #ESRW 🥳IMDEA Nanociencia 🔬👏

📢The Twitter Poster Session of the 11th Early Stage Researchers Workshop in Nanoscience is happening now! Check the contributions, comment and engage with your colleagues. The best contribution will be awarded with a prize thanks to RSEQ-STM. 👇👇👇 THREAD

It has been a pleasure to attend to MedBioinorgChem lecture!!👏👏

⁦Sonia Infante-Tadeo⁩ from ⁦IMDEA Nanociencia 🔬⁩ Piano-stool Os(II) complexes as potentiel anticancer agents #bienal2022 of ⁦RSEQ⁩

Why are Os(II)-CN half-sandwich complexes are so cytotoxic? ☠ Fast hydrolysis of Os–Z 🐢 and basicity of Os–OH2 are key. Os-CN ❤ S, and decreased TrxR activity was seen in living cells! Learn about it from Ana Pizarro, Sonia Infante-Tadeo, et al IMDEA Nanociencia 🔬 pubs.acs.org/doi/10.1021/ac…

The great cytotoxicity of Os(II)-CN complexes seems to be explained by fast aquation of Os–Z bond, basicity of Os-H2O adduct and perfect match with sulfur atoms as we observed in DMSO, cysteine or even TrxR in living cells! Discover more here👇 Ana Pizarro ACS for Authors #MyACSCover

Check out our latest article on flavin-conjugated Pt anticancer complexes! PROMOCS and Ana Pizarro groups made major contributions to this work! 🙏🙏 pubs.acs.org/doi/10.1021/ac… Inorganic Chemistry DIPC Kimika Fakultatea UPV/EHU IMDEA Nanociencia 🔬 AEBIN

Happy National Postdoc Appreciation Week at UCSF! Sonia Infante Sonia Infante-Tadeo is a postdoctoral fellow in the Diane Barber lab. As a postdoc she bridges protein chemistry and cell biology to address questions on the regulation of lysosomes in cancer and neurodegeneration.

We are excited to share that Dan Van de Mark and Sonia Infante-Tadeo Sonia Infante-Tadeo will speak at the CTB Department Research In Progress Seminar! We hope to see you at the next seminar on May 17, 2024!