💥 Pub.alert : check out our latest review article with Li Tang published Nature Nano today 🤩 📖 We discuss the implications of biomechanically regulated #immunosurveillance in #cancer and other diseases rdcu.be/dxdQ2 🧵 (1/n)

Fantastic investigation of macrophages in primary and metastatic #breastcancer by the IdoAmitLab. Bravo to the authors! Differences of macrophages in primary metastatic sites! Are different therapeutic strategies needed? Dan Michaud, PhD & I wrote a commentary describing this work.

Excited to share our collaborative study led by Natalie J. Torok, out in Nature today! It describes how enhanced matrix viscoelasticity promotes liver cancer progression in the pre-cirrhotic liver. nature.com/articles/s4158…

Very excited to see this out in nature where we show the in vivo relevance of liver viscoelasticity in liver cancer! Thank you Natalie J. Torok for having us as part of this study, and huge congrats to first author Weiguo (Jerome), not on twitter. Congratulations to the whole team!

Immunity as biophysics at the surface of a T cell dlvr.it/T2tV66

.U.S. FDA approves breakthrough tumor-infiltrating lymphocyte (TIL) therapy for metastatic melanoma #NBTNewsBeat endeavor.moffitt.org/archive/new-br…

Qiang et al revealed cancer cells excrete protons into a polarized extracellular region, driving the pH below 5.3 Nature Biomedical Engineering. The severe acidity is toxic to T cells but not cancer cells, highlighting a tumor survival strategy against immune surveillance. rdcu.be/dAgFR

Remember, you can vote in #STATMadness once a day! Check out Wyss entries in matchups 7, 9, and 27 with work from the labs of Natalie Artzi, Samir Mitragotri, and george church. statnews.com/feature/stat-m…

🧫 Curvotaxis - this phenomenon describes the preferred migration pattern of cells. Did you know that biological cells follow universal physical principals when moving inside our body? #CellBiology #Physics Eberhard Bodenschatz Weizmann Institute ds.mpg.de/4051469/240318…

Excited to share our review on hemostatic agents, where we summarize trends in 54 approved hemostats and 75 active clinical trials. Check out this timely article - with Pfizer’s latest gene therapy for Hemophilia B approved just last week! Samir Mitragotri Zongmin Zhao BioTM_Buzz

New manuscript! Excited to contribute to the 'Hydrogels in the Clinic' series in BioTM_Buzz with Samir Mitragotri, John Clegg, and Zongmin Zhao. We hope that consolidating this information will advance the clinical translation of new technologies. aiche.onlinelibrary.wiley.com/doi/epdf/10.10…

🔬 # SB3C2024 kicks off with plenary by Umut A. Gurkan on theme of Innovations without Borders: uniting ideas, technologies & communities SB3C Organizers

Thanks Meenal Datta and Jacopo Ferruzzi for organizing the cancer mechanics session at the Summer Biomechanics, Bioengineering, and Biotransport Conference SB3C Organizers! Great seeing familiar faces and making new friends.

T cells *do* make focal adhesions, and they need them! This updates (and somewhat complicates) our view of “amoeboid” vs “mesenchymal” modes of migration. Happy to see this out!

Excited to be speaking about "monocyte migration through viscoelastic matrix" at the 2024 NIH/NCI PS-ON/CSBC Cell & Tissue Mechanics Special Interest Group Seminar Series @ 2 pm ET today. Looking forward to the Q&A! Thanks Meenal Datta & Wenjun Wang for organizing.

Such a fun time celebrating the 25th anniversary of Samir Mitragotri's lab with current members, alumni, and friends. Thank you for all the amazing impact you've had on science and all of us 🙏. Looking forward to the next 25 years!

In addition to her academic #CancerResearch, Kacey Ronaldson-Bouchard is the Chief Scientific Officer and Co-Founder of Link Biosystems, which is a biotechnology company that is developing a preclinical model for cancer drug development. labtomarket.columbia.edu/news/founders-… #NCIJI2024

Junior investigators (grad students, postdocs, & early faculty) who are building and applying novel tools to better understand cancer can attend National Cancer Institute Junior Investigator Meeting from Aug. 22-23. Registration can be found at events.cancer.gov/dcb/ji-meeting…. #NCIJI2024