Reminder: The Early Stage Dementia Support Group meets today! We hope to see you there! LexKy Social Services AlzKYIN Bluegrass AAAIL AgeFriendlyLexington

It's in vivo clearing week: In Vivo Optical Clearing of Mammalian Brain biorxiv.org/content/10.110… Not with Clearitos but dextran-aCSF (and others)

I love the amount of glial metabolism papers I’m seeing these days!!! 🤩🤩

Pet marked safe during the debates.

Hardest things about moving a lab- mom tax. Learning all about schools, sports pipelines, doctors (w/o year waitlists), carpools, etc. The older you or kids get, the harder it is… and the more important it becomes! If your partner handles this mental load, thank them. A lot.

Are you using isotope tracers in your basic or clinical research? Do you want to learn how you can take this research to the next level? Do you want to find out why they call Nashville "Music City"? Come join us in November for a week of tracers and two-step!

The anti-aging impact of metformin (randomly assigned, with controls) in male monkeys after 40 months of treatment, a pan-omic clock assessment —~6 year regression of brain aging, with prevention of atrophy and enhanced cognitive ability —minimal effect on blood sugar —evidence

Metformin decelerates aging clock in male monkeys cell.com/cell/fulltext/…

I did not earn a PhD to be broken in a place where people don’t think I belong or shouldn’t speak up for myself and others.

Wow! What a powerhouse line up of speakers for Gustavus Adolphus College Nobel Conference on Sleep! I especially appreciate the dual focus on science & justice. Hersey! Stickgold! Carskadon! Nedergaard! Sehgal! Brown! Free & open to the public. October 1 - 2 gustavus.edu/events/nobelco…

Mark this in your agenda! ApoE and lipids, lipids and ApoE.

This is really interesting study on endothelial glucose transport, macrophages, and insulin resistance in muscle. I wonder how much of this is mirrored in the brain?

Saw a beautiful rainbow from my back deck today, had the BEST convo with a collaborator, and somebody just gave me a slice of free pizza. This is like a triple crown win in academia!

🤩🤩🤩🤩

The molecular basis for metformin hydrolysis to guanylurea as the primary pathway for metformin biodegradation Nature Communications nature.com/articles/s4146…

Excited to play a small role in this wonderful work by Xiaodan Wang and team in Adam Bauer lab! Cool tech, cooler findings. Spatiotemporal relationships between neuronal, metabolic, and hemodynamic signals in the awake and anesthetized mouse brain cell.com/cell-reports/f…

For the astrocyte aficionados wondering how to extract Ca2+ data from their 2P recordings - we hope this will be useful. Fantastic work put together by Yifan Wu and Miko Dai and further improved by reviewers! sciencedirect.com/science/articl…

Metformin, in people with T2 diabetes already taking this medication, was associated with a reduction in risk of developing #LongCovid and mortality 6 months after an infection diabetesjournals.org/care/article-a…

Collabs with your science besties are the BEST collaborations to have!!!

Super excited to share our work: inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia. nature.com/articles/s4159… 1/6