A preoperative model and dichotomous criteria to determine the risk of futile pancreatectomy were developed. Results show the ability to predict futile pancreatectomy could help select patients for up-front resection or neoadjuvant therapy. ja.ma/3yaUnsW

If I was his opponent, I would cry foul & file a suit claiming that I was confronted by an unnatural opponent who possessed three arms… 😳 👍🏽💪🏽🇮🇳 x.com/thebetterindia…

Select your patients with periamp cancers for adjuvant therapy- A match-pair analysis from 8 institutions (The MIPPAP study) - HPB hpbonline.org/article/S1365-… Shailesh V. Shrikhande Manish S Bhandare bhawna sirohi @SupriyaChopra Viraj Lavingia

Manish S Bhandare Annals of Surgery Shailesh V. Shrikhande Tata Memorial Hospital Dr.Vikram Chaudhari Anant Ramaswamy Prabhat Bhargava, DM (Medical Oncology) Akshay Baheti Subhash Yadav Dr.RaviChandra Reddy Key findings of the study....Thread👇

Manish S Bhandare Annals of Surgery Shailesh V. Shrikhande Tata Memorial Hospital Dr.Vikram Chaudhari Anant Ramaswamy Prabhat Bhargava, DM (Medical Oncology) Akshay Baheti Subhash Yadav Dr.RaviChandra Reddy Factors for poor OS T stage, Margin +, LN +, PNI, poor diff, PB subtype Factors for poor RFS T stage, LN +, poor diff, PNI, adj tissue invol Recurrences high [251/572 (61.7%), distant > local) Adjuvant therapy benefits 5-year OS (adj vs no adj) - 40.4%, vs. 32.3% (p – 0.012)

Manish S Bhandare Annals of Surgery Shailesh V. Shrikhande Tata Memorial Hospital Dr.Vikram Chaudhari Anant Ramaswamy Prabhat Bhargava, DM (Medical Oncology) Akshay Baheti Subhash Yadav Dr.RaviChandra Reddy How well did CA 19-9 perform in predicting recurrence? Static as well as dynamic CA 19-9 parameters used ‘Serial rise’ or ‘first raised value > 200’ are almost always associated with recurrence Relative rise of CA 19-9 is an important dynamic parameter.

Manish S Bhandare Annals of Surgery Shailesh V. Shrikhande Tata Memorial Hospital Dr.Vikram Chaudhari Anant Ramaswamy Prabhat Bhargava, DM (Medical Oncology) Akshay Baheti Subhash Yadav Dr.RaviChandra Reddy Rise in CA 19-9 precedes radiological recurrence by 4.04 months Recurrence detected by CA 19-9 rise -->Early therapy -->survival benefit Recurrence detection after CA 19-9 elevation has better survival than recurrence detection without elevation (12.8 vs 7.6 months, p – 0.005)

BALCO Medical Centre, New Raipur is hosting d annual Cancer Conclave (September 20-22) Join us for Live surgery - Whipple Procedure & Radical Gastrectomy + D2 Lymphadenectomy by Prof Shailesh V. Shrikhande & Prof Manish S Bhandare from Tata Memorial Hospital, Mumbai. Reg link - t.ly/2mR0a

LAPC cases post-chemotherapy can pose significant challenges. In such situations, total pancreatectomy with vessel divestment may be the necessary option for salvage. Grateful to Shailesh V. Shrikhande Manish S Bhandare and their team for inspiring us to take on such complex cases.

It’s time for “site-specific” prediction of CR-POPF after PD! Our latest publication in the Annals of Surgery demonstrates that the 2-factor ISGPS Classification of High-Risk Pancreas underperforms in predicting the risk of CRPF in periampullary tumours. Shailesh V. Shrikhande

BALCO Medical Centre, New Raipur is hosting the Annual Cancer Conclave on Sep 20-22 2024. Live surgery by Shailesh V. Shrikhande & Manish S Bhandare Hands-on Workshops on Lap Bowel Suturing & HJ-PJ Anastomosis on porcine pancreas supported by Ethicon and conducted by Dr. Saneya