Safety and efficacy of rapamycin on healthspan metrics after one year: PEARL Trial Results medrxiv.org/content/10.110…

Aging, cancer, and inflammation: The telomerase connection. The goal is to promote healthy aging and extend health span while minimizing the risk of oncogenesis. mdpi.com/1422-0067/25/1…

Metagenomic Analysis Reveals Large‐Scale Disruptions of the Gut Microbiome in Parkinson's Disease. …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…

Biological aging mediates the association between periodontitis and cardiovascular disease: results from a national population study and Mendelian randomization analysis. …lepigeneticsjournal.biomedcentral.com/articles/10.11…

"Physical activity benefits cognitive function and depressive symptoms in the elderly. Both “Weekend Warrior” and regular exercise patterns improve cognition in non-depressed seniors." sciencedirect.com/science/articl…

Metformin prevents brain atrophy, elevating cognitive function in aged male primates. Metformin slows the pace of aging across diverse male primate tissues. cell.com/cell/abstract/…

Lifelong elite endurance exercise might increase the risk of atrial fibrillation later in life, but it also improves fitness, survival, ventricular function, and protects against disability. journals.physiology.org/doi/full/10.11…

"While male athletes experienced a mostly favorable lifespan extension, with an increment of up to 8 years across different sports, female athletes had limited and scarce data thus limiting our ability to draw definitive conclusions about this association" link.springer.com/article/10.100…

The Cellular and Molecular Basis for Planarian Regeneration: Cell cell.com/cell/fulltext/…

Consistent signatures in the human gut microbiome of longevous populations. tandfonline.com/doi/full/10.10…

Ambient ultraviolet radiation as a cardioprotective factor: A global and regional analysis. onlinelibrary.wiley.com/doi/10.1002/hs…

Analysis of the senescence‐associated cell surfaceome reveals potential senotherapeutic targets onlinelibrary.wiley.com/doi/10.1111/ac…

Particulate matter 2.5 accelerates aging: Exploring cellular senescence and age-related diseases. sciencedirect.com/science/articl…

Vitamin D as a modulator of molecular pathways involved in CVDs: Evidence from preclinical studies. Vitamin D in cardiovascular health and its potential as a preventive/therapeutic strategy in CVDs. sciencedirect.com/science/articl…

117-year-old woman who survived world wars, Spanish Flu, Covid shares secret of her longevity hindustantimes.com/trending/117ye… via Trisha Sengupta

Molecular Mechanisms of Autophagy Decline during Aging mdpi.com/2915226 #mdpicells a través de Cells MDPI

miR-29 is an important driver of aging-related phenotypes. nature.com/articles/s4200…

The brain aged more slowly in monkeys given a cheap diabetes drug nature.com/articles/d4158…

Topical ABT-263 (navitoclax) treatment reduces aged skin senescence and improves subsequent wound healing biorxiv.org/content/10.110…

Could plasma protein levels be a surrogate for VO2 max testing as a measure of cardiorespiratory fitness? A proteomics model may provide an alternative method for estimating risk of mortality and chronic disease. peterattiamd.com/proteomics-and…