Radek Nowak
@rpnowak
Professor @UniBonn. Former @DanaFarber @harvardmed | Targeted Protein Degradation | Chemical and Structural Biology | @UniofOxford alumni. Tweets are my own.
ID: 2223370081
https://www.nowak-lab.com/ 30-11-2013 16:19:02
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Marcin J. Suskiewicz Moritz Hunkeler Shourya S Roy Burman Katherine A Donovan Hojong Yoon Radek Nowak Mikołaj Słabicki 🇺🇦 Fischer Lab DrawImpacts Molecular Cell Harvard Cryo-EM Center for Structural Biology SBGrid: Structural Biology Software Harvard Med BCMP Dana-Farber Cancer Biology Department Dana-Farber Chemical Biology Program Centre for Targeted Protein Degradation Fusion Conferences Last but not least, a paywall-free link to our paper can be found below: kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2… 18/18
We know drugs can induce protein #polymerization (BI-3802 - #BCL6). Now we know that BTB containing proteins do that endogenously! Great to have been part of this endeavor: sciencedirect.com/science/articl… And a co-publication of Marcin J. Suskiewicz lab: cell.com/molecular-cell…
Ever wondered how (often) inhibitors degrade their targets? Then you should check out our latest preprint : “Inhibitor-induced supercharging of kinase turnover via endogenous proteolytic circuits”, led by the fantastic natalie_scholes biorxiv.org/content/10.110… explanation 🧵👇
Excited to share our latest preprint on developing the first selective class IIb HDAC #degraders! Thrilled to see the #TPD community growing in Bonn Radek Nowak Christian Steinebach ! Huge congrats to first author Shiyang Shiyang Zhai and the entire team! - go.shr.lc/3LqRQhm
Great to have been part of this project with Finn K. Hansen with Dominika and Jan Gerhartz stellar team. #BonnTPD #HDAC #PROTAC
Thrilled to share our labs latest work, now online Cancer Cell where we used positive-selection CRISPR screening to discover that POU2F3 is regulated by the mSWI/SNF complex cell.com/cancer-cell/fu… 1/
Exciting double #polymerisation seminars this week! Join us on Thursday, July 25th at 11 am EDT to hear the duo of Jiho Park and Paul Park from Dana-Farber as well as Marcin J. Suskiewicz from CNRS 🌍 talk about homomerising transcription factors. 👉 bit.ly/3OmMRjp
Enable Cluster in Frankfurt, PROXIDRUGS and TheraNova invite you to the 1st Symposium on Advances in Therapeutic Approaches taking place on December 5th & 6th at Goethe-Universität. Don't miss out on this opportunity and register now! HMWK Hessen Fraunhofer-Gesellschaft BMBF
A new paper from Benjamin Ebert, Nathanael Gray, Eric Fischer, Fischer Lab, Yen-Der Li, Michelle Ma, and Muhammad Murtaza Hassan reports a trans-labeling mechanism “template-assisted covalent modification”, which enables proximity-driven pharmacology rdcu.be/dPzUW
Happy to share the latest tricks of the CalpL protease, which turns out to be a ring nuclease, too. A great team effort by Sophie Binder, Niels Schneberger, Maximilian Schmitz, Christophe. Rouillon and Marianne Engeser. academic.oup.com/nar/article/do…
Great to be part of it at Uniklinik Bonn Rheinische Friedrich-Wilhelms-Universität Bonn. We are taking on yet to be drugged transcription factors important in inflammation. #MolecularGlues #PROXIDRUGS
Congratulations to Ben Ebert - what an amazing person at the helm of the Dana-Farber Cancer Institute. Go Ben! Dana-Farber