van Heesch Lab
@vanheeschlab
Lab account of the van Heesch Group @PrinsesMaximaC for Pediatric Oncology in Utrecht.
RNA systems biology, translated ORFs & immunotherapy target discovery
ID: 1277339663787843589
https://research.prinsesmaximacentrum.nl/en/research-groups/van-heesch-group 28-06-2020 20:34:57
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Interested in the fascinating field of microproteins? Join my group in a collaboration with Sebastiaan van Heesch at the PMC. PostDocs apply below: werkenbijprinsesmaximacentrum.nl/en/vacancy/pos… HeckLab PrinsesMáximaCentrum
.Sebastiaan van Heesch is benoemd tot junior Oncode Institute onderzoeker 👏 Hij gaat kijken naar micro-eiwitten, hun rol in het ontstaan van kanker, en hun potentieel op het gebied van nieuwe immunotherapieën voor kinderkanker. Gefeliciteerd! research.prinsesmaximacentrum.nl/nl/news-events…
Had a great time presenting our van Heesch Lab & John Prensner lab work on the “dark proteome” at the #DarkGenome 2023 symposium in London. Great setup for a meeting, met many new people, received good feedback. Thanks Enara Bio Nucleome Therapeutics ROME Therapeutics for organizing & inviting me!
We recently announced that ten Junior Investigators and their research groups are invited to join Oncode Institute per January 1st, 2024. In the coming period, we will introduce them all to you! Meet Sebastiaan van Heesch, van Heesch Lab from PrinsesMáximaCentrum research.prinsesmaximacentrum.nl/en/news-events…
New research in Molecular Cell shows the important role of micro-proteins in the childhood brain tumor, medulloblastoma. The findings could in future lead to new, targeted treatments tackling the disease at a molecular level van Heesch Lab Michigan Medicine ➡ research.prinsesmaximacentrum.nl/en/news-events…
Interesting new article in Molecular Cell describing noncanonical open-reading frames (ORFs), microproteins and the translatome in cancer cell survival. While the example is medulloblastoma, it will be important to study in different tumor types👇 Translation of non-canonical
NEW PAPER👇 How do microproteins orchestra cancer? Check it out and see for some nifty work in #medulloblastoma. So proud of Damon Hofman J Ruiz Orera and Sebastiaan van Heesch for collaboratively leading this work, now out in Molecular Cell University of Michigan Michigan Medicine U-M Rogel Cancer Center UMich RNA Center 〽️🧬
A beautiful study emphasizing the importance of non-canonical ORFs and the encoded microproteins in cancer research. Elegant CRISPR screens identify a microprotein necessary for medulloblastoma cell survival. Congratulation John Prensner and Sebastiaan van Heesch!
What a great way to start 2024: Damon Hofman’s first co-first paper in our group got published today at Molecular Cell. Fantastic collaboration with J Ruiz Orera & John Prensner, plus all others involved! PrinsesMáximaCentrum
Thrilled to see our latest paper published in Molecular Cell! It has been a joy to work on this exciting research on the role of microproteins in #medulloblastoma, a collaboration led by Damon Hofman Sebastiaan van Heesch (van Heesch Lab) and John Prensner. 👇
Beautiful study by Sebastiaan van Heesch and John Prensner ! clever CRISPR tiling for functional uORFs👏👏👏 cell.com/molecular-cell…
Very interesting findings, a subset of translated uORFs that maintain cancer cell survival. Agree with your recommendation for the inclusion of non-canonical ORFs in cancer genomics studies. Well done to all involved Damon Hofman, J Ruiz Orera, Sebastiaan van Heesch, John Prensner... #Riobseq