Standing up for the university | Nature Human Behaviour nature.com/articles/s4156…

Teaching students to interpret data and write their first scientific paper can be hard!
Our new publication provides all the materials you need to teach these skills in graduate or upper-level undergraduate courses. 1/
doi.org/10.24918/cs.20…

From bench to bedside... 🤯🫥

Did you miss last week's seminars? Videos are now up on our youtube! #FragileNucleosome

Wow - just noticed that we've passed 50,000 views on our youtube channel! Thank you so much to all the speakers and organizers over the years! Dr. Christine Cucinotta @[email protected] Pravrutha Melvin Noé González Teif Lab Hanneke Vlaming Ben Martin Matteo Perino XiaoliWu 吴小丽 Ulduz Sobhiafshar
youtube.com/@FragileNucleo…

There's still time to sign up for this Wednesday's seminar! Join us to hear about histone modifications, gene regulation of microglial memory from Rafia Akhlaq and Annie Vogel Ciernia!

Register here: harvard.zoom.us/webinar/regist…

So excited to host these two speakers next week! Come and join us to listen to histone modifications, gene regulation of microglial memory!

(1/4) #preprints

Latest work from postdoc hero Samuel Corless is now online

We analyzed tens of thousands of publically available ChIPseq data sets for their distributions at repetitive regions and focus on centromeres.
biorxiv.org/cgi/content/sh…

I love this 💕 and 🤯😳

“…we efficiently converted the XY chr. set to XX without an additional Y chr… we differentiated induced iPSC from the tail of a sexually mature male into fully potent oocytes, which gave rise to offspring after fertilization” nature.com/articles/s4158…

Missed some of the last few seminars? Videos are up for the semianrs from Dheva Setiaputra, Nikhil Hajirnis, A. Xiyal Mukund, and Ezgi Karaca!
Watch them all on our youtube channel: youtube.com/@FragileNucleo…

Important correction: The talks tomorrow start at 4pm and not 5pm UK time due to the clocks having already changed in the US!

It took my 25 tweets to share this, but if that (or the manuscript itself) is too long - here is the synopsis in 17 syllables for Chromatin Haiku:

At most promoters
P400 compensates
For loss of SWI/SNF

#ChromatinHaiku
biorxiv.org/content/10.110…

In case anyone missed the original post a while back, here is a *FREE* BioRender equivalent that has image assets compatible with InkScape and other illustrator platforms.

bioicons.com

Party mood at +4 :)

In our new preprint by Ryan Samuel et al. we used hPSCs to find developmental sources of heterogeneity in human melanocytes. Signature genes in melanocytes that emerge from the Schwann cell lineage promote metastasis in melanoma. biorxiv.org/content/10.110…