Exiting findings linking oncogenic Ras and miRNA activity from Bing Shui in Kevin Haigis Lab. Paper just out in Molecular Cell. Happy we were able to contribute in small part to this work. Oncogenic K-Ras suppresses global miRNA function sciencedirect.com/science/articl…

Excited to share my PhD work Kevin Haigis Lab studying the interplay between oncogenic K-RAS and global miRNA function, out today Molecular Cell ! We found that oncogenic K-RAS suppressed global miRNA function and here is a brief tweetorial: (1/14) authors.elsevier.com/c/1hM64_OylrlC…

Our new paper “A molecular proximity sensor based on an engineered, dual-component guide RNA” is out! We describe a strategy named “P3 editing” for controlling genome editing with Protein-Protein Proximity in human cells. Thread: (1/9) biorxiv.org/content/10.110…

The next VESS seminar Sept. 5 promises to be as engaging as it will be informative. Atlas of Variant Effects Alliance Xiaoyi Li Florian Wünnemann brotmanbaty.org/events

Thrilled to share our work profiling Ale yeast protein dynamics across fermentation and serial repitching! biorxiv.org/content/10.110… Maitreya Dunham Edward Marcotte Live Oak Brewing Co. #BeerYeast #SystemsBiology #Proteomics Sneek Peak thread🧵 below

Congrats Sanjay Srivatsan 🤩🤩🤩 If you are interested in dev bio and new technologies, join this fantastic lab!

We (with wei yang and Jay Shendure) are thrilled to announce our new paper on the "human RA-gastruloid" model, showcasing morphologies and transcriptomes akin to E9.5 (mouse) or CS10-11 embryos (biorxiv.org/content/10.110…). (1/n)

A great thread to read :)

Excited to share our new work!!🥳How do cells lose totipotency to fate segregation? w Zernicka-Goetz Lab we found that early blastomeres experience a "Composite State" by displaying dual-lineages signatures! Link for full text👉: rdcu.be/dITfo

Congrats Nobu Hamazaki wei yang !!!

Very happy to share our latest w/ Devin Schweppe and Nobu Hamazaki labs, where we map the temporal dynamics and proteomic landscape of mammalian gastruloids. Sneek Peak 🧵below #stembryo #gastruloid #proteomics biorxiv.org/content/10.110…

🎉 Congrats!