Thrilled to share Bangyan Xu's latest manuscript in which he discovered that cathepsin X is transcriptionally upregulated during dendritic cell maturation in response to TLR agonism. MinternLab Beth Anderson Bio21 Institute #LEMLab doi.org/10.1111/imcb.1…

How do combinatorial histone modifications impact gene expression? Our latest research aims to unravel this mystery. By engineering a mutant LSD1 enzyme (Y391K), we've disrupted the crosstalk between H3K4me and H3K14ac to explore its role in gene regulation. Check out our study!

Huge congrats to Chuanyun Xu and all collaborators Broad Proteomics Alice Ting Shuo Han Wu Tsai Neurosciences Institute HHMI HHMI | Janelia! (Sneak in an ad: my lab at Janelia is seeking a highly motivated postdoc interested in kidney physiology. Pls share!) cell.com/cell/fulltext/…

The final version of our #bioorthogonal #lipidtime method for imaging rapid inter-organelle transport of fluorescent phospholipid analogs is now published — congrats to Lin Luan (Lin_Luan), Dongjun Liang, Dylan Chiu, & Reika Tei! doi.org/10.1021/acsche…

A big shot on Nature Nature Chemical Biology 🥳 Introducing innovative methods to distinguish KL-la from its isomers, showing its crucial role in cellular metabolism and Warburg effect! Congrats to co-first author Zhijun(Andrew) Zhu and everyone on this collab with Zhao lab ✨ nature.com/articles/s4158…

Congrats Liron and the team on the molecular COUPLrs!

We are searching for a talented administrative assistant to be a key member of our team Koch Institute at MIT. Please share widely! #hiring #sciencejobs careers.peopleclick.com/careerscp/clie…

Such a comprehensive story! Really inspiring to see how new techniques like AlphaFold-Multimer can help mechanistic studies. Congratulations Juntao!🥳

The Weeks Lab UW–Madison Biochem is hiring at all levels! Broadly, our lab uses engineered enzymes to decipher cellular signaling to advance biological discovery and therapeutic development. If this sounds exciting to you, please reach out! Reposts appreciated. 🧪weekslaboratory.org

Targeting two proteins on the same cell surface via bispecific antibodies is enabling exciting opportunities for novel modes of therapeutic action in the clinic. In this review we highlight their growing impact from early discovery to late clinical stage. authors.elsevier.com/a/1jYkN8jWWJxM…

The Morstein Lab will be hiring on all levels - please reach out if you want to chat science or are interested in joining! (3/3)

Glad to share our latest study on the cell-surface proteome of human dendritic cells, by our awesome long-term collaborators Namrata and Charles Broad Proteomics and talented undergrad zuzhi jiang (soon at UC San Francisco tetrad for PhD). journals.aai.org/jimmunol/artic…

Are you looking to perform research with a great scientist at a world-leading institution? Here is an opportunity to work with Johannes Morstein at Caltech on the PhD or postdoc level. The research will be centered around chemical biology in the human lipidome. morsteinlab.caltech.edu

So excited to to share our lab's photosensitizer proximity labeling platform, POCA, which combines Janelia Fluors (thanks Luke Lavis!) with HaloTag and cholesterol-based probes to define the intracellular cholesterol interacting proteome. Congrats to Andrew Becker and team!

Thrilled to share that I will join Johns Hopkins University Johns Hopkins BME as an Assistant Professor in 2025! The Yang Lab will develop novel bioelectronics and biomaterials for brain-machine interfaces, regenerative medicine, and the study of human neural development and diseases.

Check out my piece on the recent papers describing an H3-H4 chaperone role for the Fork Protection Complex component Mrc1. Congrats to Moazed Lab, The Groth Lab, Thon, and Jia labs! The awesome power of yeast coupled with AlphaFold2-multimer! cell.com/cell/abstract/…