Aarhus Uni.hospital har i dag præsenteret en visionær plan for opførelsen af et nyt Dansk Neuroforskningscenter (DNC) bit.ly/3Jd8nTq Today, Aarhus Uni.hospital presented a visionary plan for constructing a new Danish Neuroscience Center (DNC) bit.ly/3JcSdcp #sundpol #dkvid Jens Christian Hedemann Sørensen

Pericytes sense #glucose #metabolism via #Katp channels and signal upstream to #precapillarysphincters to open for blood perfusion.

I was really glad to present our work on the effect of Carbonic Anhydrase Inhibitors in Alzheimer’s Disease Model at the #BRAIN2022! ⁦Alzheimer's Association⁩ ⁦@BRAIN_2022⁩ ⁦CFIN 🧠⁩

📣I am thrilled to share our preprint: "FDA-approved carbonic anhydrase inhibitors reduce Amyloid β pathology and improve cognition, by ameliorating cerebrovascular health and glial fitness" A big shout out to Silvia Fossati's team and collaborators!!! biorxiv.org/content/10.110…

Check the new issue of Awake Functional Imaging of Small Animals in Frontiers, where my student @Smdk_184 shows a novel approach for serial imaging in mice using MRI and optical imaging! Good job! CFIN 🧠 frontiersin.org/research-topic…

Capillary stalls & pericyte constriction behind the impairment of neurovascular coupling in penumbra after #stroke. Great job Christian Staehr!

#Capillary flow stalling in the #brain before and after #stroke #reperfusion measured by #OCT. Can't wait to present these results at #Europhysiology this week. Pls #RT! Check out our preprint: biorxiv.org/content/10.110… Scandinavian Physiological Society, The Physiological Society, #NeuroTwitter #Europhysiology2022

Precise optogenetic control of brain arteriole diameter in vivo. A way to probe vascular networks like a "circuit board" during studies of cerebral blood flow regulation. Collaborative work spearheaded by Philip O'Herron of Augusta University. elifesciences.org/articles/72802

Exciting talk by Rune Enger on their latest research published by Laura Bojarskaite and colleagues about astrocytic calcium signaling and 🧠blood flow! Thanks for visiting CFIN 🧠/Aarhus Universitet. #BrainHygge Eugenio Gutierrez

Present at #ESM2023 with our results showing the prevention of capillary disturbances by carbonic anhydrase inhibitors! Silvia Fossati David Boas Leif Østergaard Alzheimer's Association

Our article is now published online! We tested for the first time in a model of AD and cerebral amyloid angiopathy (CAA), the carbonic anhydrase inhibitors (CAIs) methazolamide and acetazolamide, FDA-approved against glaucoma and high-altitude sickness. Results (see comments):

Great article featuring our recently published manuscript on the protective effects of carbonic anhydrase inhibitors on a model of cerebrovascular amyloidosis! ⁦Temple University⁩ ⁦@BioBuzzMaryland⁩ linkedin.com/posts/fossatis…

Monocyte-derived IL-6 programs microglia to rebuild damaged brain vasculature | Nature Immunology nature.com/articles/s4159…

Present at #AAIC2023! Come to my poster #676 where we can discuss our finding of early capillary dysfunction in Th-SwDI mice and it’s prevention by carbonic anhydrase inhibitors!

Interested in the microcirculation? 👇 Pericytes in the brain and heart: functional roles and response to ischaemia and reperfusion academic.oup.com/cardiovascres/… CFIN 🧠 HealthAU

Amazing!