Western blot

Excited to share our paper in Nature Biotechnology. We've developed a CAR-Enhancer (CAR-E) that enhances the activity and persistence of CAR T-cells. These memory CAR T-cells can re-expand months later. Here's a brief summary: go.nature.com/3SuUgj3

So psyched to help organize and take part in this focused meeting on advances in cell therapies for solid tumors. Abstract submissions open in mid-September. Please save the date!

PI back at the bench for the one thing he still can do better than anyone else

🚨An entire meeting dedicated to innovation and progress in solid tumor cell therapy!🚨 On behalf of my co-organizers and Society for Immunotherapy of Cancer, please save the date and spread the word! #ChristineBrown Jennifer Guerriero, PhD John Haanen Daniel Powell Lab @ UPENN Evan Weber #TIL #TCR #CAR #Synbio

Excited to share 'frugal' CRISPRkit, a gene editing tool for K-12 education! Developed almost entirely by high school and undergrad students, led by Marvin & Matthew, this kit brings hands-on CRISPR experiments to classrooms to explore genome engineering without equipment. (1/2)

rejected after the second round of revisions

Well-deserved A/Prof Paul Beavis sellmyerlab and the other awardees!

We are hiring! Apply for this postdoc position in @Pauloslab. We seek to work with immunologists eager to build our cellular therapy program. We generate novel CAR, TIL and TCR cell products to kill solid tumors! faculty-emory.icims.com/jobs/132570/po…

Very happy to share this new work on LAG3 and PD1. Has been a long road to (begin to) sort out how LAG3 functions in CD8 T cell exhaustion. Great work by Shin Ngiow and super collaboration (and 2 other great papers) with Vignali Lab and Dario Vignali cell.com/cell/abstract/…

T cells express a ton of CD5, so why CD5 CAR T cells don't kill each other? Turns out, they completely degrade CD5 protein and thus evade fratricide. Unique mechanism unveiled in a mechanistic study - and PhD thesis work - by Royce Ma: cell.com/cell-reports-m…

Our letter is out in this week's Science: Teach creativity in science! Creativity can be taught, nurtured and encouraged. Access to the space, time, and tools for creativity is crucial for the training of early career scientists. science.org/doi/10.1126/sc… night-science.org

1: we show that a simple addition of 80 mM NaCl to culture medium enhances human CD8+ T cell effector function by largely reprogramming their transcriptome and by promoting the acquisition of cytotoxic function while maintaining expression of stem-like genes

Looking for a small meeting with leaders in cell therapy discussing high impact translational research? Look no further! The UChicago Jonas Center Symposium is for you! Please get in touch if you're interested or, better yet, register and join us! cme.uchicago.edu/JCCTS2024

Excellent results with autologous CD7-PEBL CART in T-ALL from Singapore and Rome nature.com/articles/s4159…

Ok who has tips for taking parental leave as a PI, specifically for lab management? (Pls rt)