We are excited that the Swiss National Science Foundation has funded our interdisciplinary project, in which we (Christophe Dessimoz, Iñaki Ruiz-Trillo, 𝘋𝘪𝘳𝘬, Pedro Beltrao, and Dave Moi) would like to reconstruct the urmetazoan protein repertoire and interaction network.

After 5 years of an emotional roller-coaster, we are so happy to see our latest Asgard adventure published! nature.com/articles/s4158… A huge thanks to my brilliant co-first authors and friends Daniel Tamarit & mus musculus, and of course Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺! A thread 🧵.

Our latest chapter of the Asgard saga is finally published in @nature! See nature.com/articles/s4158… #OpenAccess See separate twitter threads by lead authors Laura Eme and Daniel Tamarit for background info. Below a thread on the history of the Tree of Life .

Very excited about this grant with Fasshauer_Lab 𝘋𝘪𝘳𝘬 Christophe Dessimoz Pedro Beltrao Dave Moi to reconstruct the #urmetazoan protein repertoire & interaction network using phylogenomics, proteomics, cell biology & biochemical approaches! #animalorigins #evolution

Is there an equation for calculating the number of circular permutations with 4 elements with possible repetitions? 1234 1111 1112 (= 1121 = 1211 = 2111) … I think I know the right solution but whenever I do it on paper, my number is smaller. 🤔🤷‍♂️

Have a look at the illustrated evolution of the nervous system, based partially on our review in Annu Rev Genet. annualreviews.org/doi/10.1146/an… knowablemagazine.org/article/living…

🔥Do not miss this! 🔥>10 fully funded PhD positions in Quantitative Biology Université de Lausanne Dept of Computational Biology, Uni Lausanne Center for Integrative Genomics, UNIL (CH) 🧪>💻Biologists transitioning to data-science? 💻>🧪Computer scientists looking to solving biological problems? APPLY HERE #PhDposition #PhD #phdlife tinyurl.com/4k2fz9yr

Two PhD positions available in our group (fasshauerlab.org). Join us to explore the evolution of the vesicle trafficking machinery during 1) the rise of the eukaryotic cell and 2) the emergence of the first animals. Please RT. More details at: career5.successfactors.eu/career?career%…

Very happy to have been a guest on the #bioinformatics chat podcast Roman Cheplyaka | the bioinformatics chat by Roman Cheplyaka. We talked about our recently published paper on identifying drug targets 💊🎯🧬 👇 bioinformatics.chat/drug-targets

We are hiring and have a 4-year PhD position available at the Michael Sars Centre at the University of Bergen. Topic: Functional characterization of ctenophore neurons. Reposts are highly appreciated! Michael Sars Centre Universitetet i Bergen European Research Council (ERC) #ctenophores jobbnorge.no/en/available-j…

Very happy to see the comic I made with makinaro.com on Bluesky - Comms Open republished by Scientific American today!

Off to a great start of the week with the bulk of my PhD work published on Protein Science. Briefly, using biochemical/physical and computational approaches we characterised the conformational changes regulating the Munc18-1/syntaxin-1a complex. More here: onlinelibrary.wiley.com/doi/epdf/10.10…

The lab is officially open and we are hiring at all levels! If you are interested in doing cryo-electron tomography ❄️🔬 #teamtomo with a view of the Alps🏔️, check out open positions in our new lab 👇 PhD position: bit.ly/3Tn9dUX Postdoc position: bit.ly/3V1vhpq

A postdoc position is available in our group (fasshauerlab.org). Join us to explore the evolution of the vesicle trafficking machinery during 1) the rise of the eukaryotic cell and 2) the emergence of the first animals. Please RT. More details at: career5.successfactors.eu/career?career%…

We have posted our latest work on SNARE proteins in BioRxiv. 🙂🍾 We found that there is a matching pattern in the core of the SNARE complex that dictates the position of the four fundamental SNARE types in the bundle, resulting in a QabcR complex. biorxiv.org/content/10.110…

Our latest study is available as a preprint. aysima hacisuleyman looked at the question of how protein dynamics and function can be investigated directly using the protein sequence. biorxiv.org/content/10.110…

Thanks to a number of suggestions from helpful peer reviewers, our manuscript has been further improved and has now been published in Protein Science. onlinelibrary.wiley.com/doi/10.1002/pr…

Pleased to announce our latest preprint: Genetically Encoded FerriTag as a Specific Label for Cryo-Electron Tomography. Great work of Wang Chang and Ioan Iacovache. doi.org/10.1101/2024.0… with great support of Dubochet Center for Imaging (DCI)-Bern and Microscopy Imaging Center Bern

Very proud to be part of this study led by Anna Malaspinas, published in nature, exploring the genomic history of Rapa Nui. Huge shoutout to Barbara and Victor for their amazing work! Check out our findings here: nature.com/articles/s4158…

Analyses by Barbara Mota, AnnaSapfo Malaspinas, Olivier Delaneau et al. show that the Polynesian population of Rapa Nui (Easter Island) already had a Native American admixture of about 10% before Columbus, which shows that they reached the American continent. nature.com/articles/s4158…