Proudly present the structure of the Ceramide Synthase from amazing PhD student Jan-Hannes Schäfer! great collaboration with Florian Fröhlich Caro Koerner and Lena Clausmeyer Uni Osnabrück #CellNanOs #cryoem biorxiv.org/content/10.110…

Another Preprint from the lab . Another great collaboration with the Arne Moeller. Great teamwork by first authors Jan-Hannes Schäfer, Lena Clausmeyer and Caro Körner. The structure of the yeast ceramide synthase. Another #lipidtime story. biorxiv.org/content/10.110…

We are looking for a PostDoc how wants to figure out with us how human cells use a-arrestin ubiquitin ligase complexes to selectively adjust their nutrient transporter repertoire during entry and exit from quiescence.

Fantastic opportunity for 3!! prospective new group leaders working on protein-lipid interactions and membrane biology. Come and join a high profile research environment Uni Osnabrück with CRC1557 and RTG2900. Apply now!

Interested in lipid transport proteins (LTPs)? Ever wondered how lipids bind to them? Then our latest preprint, led by Sriraksha Srinivasan and Daniel Álvarez, might be what you are looking for! Super-short thread below (1/4) biorxiv.org/content/10.110…

Cool paper from amalia megarioti Christos Gournas Florian Fröhlich identifies a set of flavodoxin-like proteins (FLPs) that generate ubiquinol at the plasma membrane (like human FSP1) and thereby protect quiescent yeast from lipid peroxidation & #ferroptosis! cell.com/cell-reports/f…

So stoked to be sharing this! New proteomics map of human subcellular architecture. CRISPR + organelle IP mass spec at scale. Check out pre-print biorxiv.org/content/10.110… and organelles.czbiohub.org. 🙌 to fantastic team Chan Zuckerberg Biohub Network SF & collabs! 1/2

Our #lipidtime story continues with yeast SPT-Orm2! Great team-work with co-first Carolin Körner from Florian Fröhlich. Arne Moeller Dovile Januliene Kristian Parey and David Teis Oliver Schmidt. #b3d #cryoEM Have a look doi.org/10.1101/2024.0…

Newest work from the lab: Structure of the Orm2-containing serine palmitoyltransferase complex reveals distinct inhibitory potentials of yeast Orm proteins. Great collaboration with Florian Fröhlich . Arne Moeller Dovile Januliene Kristian Parey and David Teis biorxiv.org/content/10.110…

Postdoc position available in ceramide synthase and lipid biology. Fröhlich Lab Uni Osnabrück. tinyurl.com/4udedvux Dive into our latest preprint: rb.gy/duvmfa. Reach out if interested or know someone. Please retweet! #Postdoc #LipidTime

🥳Our paper on Golgi quality control: The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi biorxiv.org/cgi/content/sh… #biorxiv_cellbio. Great work from Yannick Weyer, Sinead Schwabl, Oliver Schmidt

Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain | Nature nature.com/articles/s4158…

So excited that it's finally out! Congrats 🎉🎉 Eleonora for your great work and all our fantastic collaborators!!! Gasdermin D cysteine residues synergistically control its palmitoylation-mediated membrane targeting and assembly | The EMBO Journal embopress.org/doi/full/10.10…

Finally out there... Congratulations to first authors Carolin Körner and Jan-Hannes Schäfer. Thanks to the Florian Fröhlich and Arne Moeller labs for the great collaboration. check out at sciencedirect.com/science/articl…

Our #LipidTime journey continues! Final version of the SPT-Orm2 study is now published in Cell Reports. Congratulations to 1. authors Caro Körner and Jan-Hannes Schäfer, and our amazing scientific partners Arne Moeller Oliver Schmidt Dovile Januliene Kristian Parey David Teis rb.gy/nd4wju

We are looking for PostDoc with a background in redox biology, experience with cell culture models and basic microscopy imaging to study #lipid #metabolism in the context of #ferroptosis. Interested? Send me your CV and motivation letter by Sep 10th. #ZML Ferroptosis (SPP 2306)