It really does know how to use it. 😂

Structure prediction of alternative protein conformations | Nature Communications - Cfold, a structure prediction model designed to predict alternative protein conformations. - Train AF2 without the Template Track and focus on MSAs and coevolutionary signals - Predict different

Say what you will about Bill maher but he's spot on about this

Clay for fun with Cecilia Clementi. In culo alla balena!

🚀Excited to announce: Open-source AlphaFold3 implementation! 🚀 I am thrilled to announce one of the models we have been building for the last 8-weeks at Ligo - an open-source implementation of DeepMind’s frontier model, AlphaFold3! Here’s what we have learned, a thread (1/11):

Don’t be a career. Be a rainbow. Steve Jobs’ speech at Palo Alto High School graduation in June 1996. Don’t be a career. The enemy of most dreams and intuitions, and one of the most dangerous and stifling concepts ever invented by humans, is the “Career.” A career is a concept

🥳Happy to share our work on extracting extremely accurate electron densities (and many related properties) from wavefunctions. Feel honored to work with all these talented colleagues in Microsoft Research AI for Science Lab

Check out this cool work by my colleagues at Microsoft Research AI4Science, using denoising score matching to distill one-electron densities from wavefunctions!

Very neat application of score matching + noise contrastive estimation 😎 See this thread for more details

We’re presenting AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 It could help scientists better understand how biological systems function, save time in research, advance drug design and more. 🧵 dpmd.ai/3XuMqbX

Very happy to see the ATLAS Experiment (one of the big LHC experiments CERN) publishing in Machine Learning: Science and Technology !