Anna Akhmanova and myself wrote a comment for Current Biology about this publication. We put it back into the context of previous works, summarized the most convincing parts and pointed at exciting questions about MT dynamics and cell migration. authors.elsevier.com/a/1jYNi3QW8S6F…

Mitochondria (top) and microtubules (bottom) in a cell videoed through a microscope. #CellBiology

Check out our new preprint!

Excited to host Vicky Sanz-Moreno UC San Francisco tomorrow!

what drives organelle shape? Yeast vacuoles (imaged here by MaryMirvis using soft x-ray tomography) often have dimples on the surface of a characteristic curvature. What molecule creates those dimples? a reticulon-like protein that bends membrane? a wedge-shaped lipid? 1/2

We’re happy to report our study on the regulation of resection tract lengths during meiotic recombination was published today Genetics Society of America. The master meiotic kinase Mek1 slows down exonuclease I. academic.oup.com/genetics/artic…

"The authors have uncovered an elegant adaptive feedback mechanism in which microtubules function as a mechanostat by becoming reinforced in response to compression and enabling cells to orchestrate spatiotemporal contractility to squeeze the nucleus through a tight space."💪💪💪

Very happy to see our paper on using a high-throughput yeast meiosis assay we developed to screen for reproductive toxicants ( pubmed.ncbi.nlm.nih.gov/38906490/ ) has now been featured as "paper of the month" by the NIEHS in their "Environmental Factor" newsletter! factor.niehs.nih.gov/2024/9/papers/…

Characterization of open chromatin sensitive to actin polymerization and identification of core‐binding factor subunit beta as mechanosensitive nucleocytoplasmic shuttling protein dlvr.it/TCxT4B

Certainly the best movie from our lab! Bi-Chang was a master at acquiring images from the light sheet, took amazing movies of our strains. Still so much to learn about the basic process of cell division! Thanks for working with us!

It's a long journey, and the effort has made this true. We discovered a homeostatic feedback loop between E-cadherin and EGFR that regulates intercellular viscosity during collective cell migration. | PNAS pnas.org/doi/10.1073/pn…

Excited to share that my latest research on rejuvenating aged oocytes has just been published in Nature Aging with Springer Nature! 🌟 Read here: x.com/NaturePortfoli…

The high point of any graduate program retreat has to be the Booth-Buchwalter cocktail party. Young faculty like this give me hope for the future. David Booth Abby Buchwalter