opioid poisoning trends in Newcastle,NSW from early 90’s #EAPCCT2023 ⬇️heroin since very early 00’s ⬇️codeine following TGA Australia up scheduling 2012ish ⬆️oxycodone and methadone ⬆️ICU admissions …reflecting ⬆️ in long acting opioids/naloxone infusion use 🤔 Katherine Isoardi 👏🏼👏🏼

Aussie colleagues show drop in codeine since scheduled, rises in oxycodone and methadone exposures. Fentanyl only 1%- from US, the fentanyl capital of the world (?) I hope for them it doesn’t take off, but suspect it will. #EAPCCT2023

Opioid Deprescribing Guideline launched! The why, when, (when not) & how to #deprescribe opioid analgesics based on the best evidence Here: tinyurl.com/3exa372h NHMRC ACSQHC Australian Deprescribing Network (ADeN) ASCEPT Sydney Health #Proud Aili Langford Danijela Gnjidic Carl Schneider & team

AI in toxicology… TOXNET or SkyNET … better at diagnosis. But isn’t Clin Tox a risk assessment speciality? EAPCCT #eapcct2023

Airway management of patients presenting with drug overdose #Opinion doi.org/10.1111/1742-6… Katherine Isoardi Gerben Keijzers Wiley Clinical Health ACEM

less than6 weeks till #acemws23 in #Newy 😃 with some great keynote speakers ⬇️ of course the highlight will be the pre conference Toxicology workshop on Tuesday 18th July with Geoff Isbister and Úna Nic Ionmhain 😉 rego here acemws2023.com/registration-3/

In adults who ingested acids, computed tomography (CT) performed well for diagnosing transmural gastrointestinal necrosis. The CT scans in this study were interpreted by a panel of subspecialty radiologists. tandfonline.com/doi/full/10.10…

What happens when a patient prescribed weekly oral methotrexate mistakenly takes it daily? Colleagues at Calvary Mater Newcastle, NSW illustrate the outcome. Geoff Isbister doi.org/10.1080/247343… TAPNA Inc. AACT American College of Medical Toxicology EAPCCT

Rules around psychedelics are about to change, and an unsurprising player is entering the m… ⁦ abc.net.au/news/2023-06-1…

alcohol/substance intoxication=commonest cause of adult,severe ABD in ED ⬇️nsw guideline summary below toxicology workshop 18/07/23 #acemws23 includes an interactive discussion around all aspects of care for this group ➡️faculty includes toxic nurse extraordinaire Maree

Snake envenomation is a WHO designated Neglected Tropical Disease. Rmaah Memon, MD Harvard Toxicology Charlotte Goldfine describe the situation snakebite in rural Pakistan and illustrate that the challenges extend well outside the tropics. doi.org/10.1080/247343… The Snakebite Foundation

A solid 4h morning with MPhil and PhD students in Anuradhapura with Anjana …from in vitro neurotoxicity in krait envenoming to community measures to prevent snakebite Anjana Silva

The 2023 APAMT scientific meeting will be in Kerala in India 🇮🇳 November 6-10, 2023 ➡️ programme will be interesting and varied as always ➡️more info apamt2023.com Victoria Stephen Justine Athieno Asanka Migelheva

#ToxABC Thanks to the suggestion of Geoff Isbister, this week’s ToxABC will be on…joules (as in electricity)! Not really a chemical, but joules may serve as “medicine” as well, for instance to resuscitate patients with toxic arrhythmias.

Just under 3 weeks till #acemws in Newcastle ⬇️Finalsed Toxicology workshop final programme conference and workshop rego here ➡️acemws2023.com/registration-3/ ACEM Geoff Isbister Úna Nic Ionmhain Maree

#OpioidPoisoning doi.org/10.1111/1742-6… #OpenAccess @Kisoardi Geoff Isbister Wiley Clinical Health ACEM

✉ gsEAPCCT.org eapcct.org @eapcct @AACTtinfo @AAPCC American College of Medical Toxicology APAMT MENATOX SOT AACT Acute & Intensive Care

Among patients who received Indian polyvalent antivenom, acute reactions were common, including anaphylaxis (19%) and serum sickness (4%) tandfonline.com/doi/full/10.10…

A long time to do and thanks to NHMRC Clinical Toxicology a placebo RCT of antivenom in snakebite; early antivenom versus reactions to antivenom pubmed.ncbi.nlm.nih.gov/38913734/