How do coacervates direct the outcome of (bio)chemical reactions? We developed a model to predict their effect on bimolecular, polymerization, self-replication and oscillating reactions, to guide experiments. Exciting results for origins of life & biology! chemrxiv.org/engage/chemrxi…

Great collaboration with Dr Zoë Waller and Dr Ke Li in Exeter! Hope it will benefit the community 😊 iM-Seeker: a webserver for DNA i-motifs prediction and scoring via automated machine learning academic.oup.com/nar/article/do…

Thorough discussions would always benefit a field. Never the opposite. Reflections on prior work like this are gold for our field. 🫡 It's astonishing to me that the prior work has missed the camera shot noise and rather just used Gaussian noise.

Turns out pretty much any condensate that binds actin can polymerize and bundle actin filaments! Congrats to grad student Caleb Walker! Liquid-like condensates that bind actin can polymerize and bundle actin filaments biorxiv.org/content/10.110…

Riboswitches integrate all types of cellular signal, from ligand binding to transcription factor regulation. Check our newly published work in Nature Communications from Nils Walter Lab nature.com/articles/s4146…

Biomolecular condensates with complex architectures via controlled nucleation: nature.com/articles/s4428…

Wow, @nature has retracted the 2020 Poore et al. cancer microbiome paper that we showed (journals.asm.org/doi/10.1128/mb…) was deeply flawed. The retraction date is tomorrow so I can't yet read the official notice, but I'll update when I can Retraction Watch Professor Booty PhD

In our new review paper, Yue Wan and I focused on the functional importance of RNA structure in gene regulation. Many thanks to Yue and Xinang! I really enjoy the writing process. nature.com/articles/s4158…

Excited to launch our cloud-based image analysis platform today at nimbusimage.org! Analyze and interact with your data, all in the browser. Follow sign-up instructions to request an account.

Excited to share that our paper on transcription repression after DNA double-strand break is online. Great collaboration with ⁦Taekjip Ha⁩ and ⁦Yang Liu⁩, spearheaded by Shuaixin He ⁦Biophysics Dept@Johns Hopkins Med⁩ ⁦BCMB Graduate Program at JHMI⁩ cell.com/cell-reports/f…

Oxford nanopore sequencing

Wow fundamental change of how we should view condensates' function, showcasing that's it IS possible to test the direct function of phase transitions.

It was my great honor to write this The RNA Society #Spotlight article featuring Robert Ietswaart ! Anyone interested in quantitative biology, mathematical modeling, and a path to entrepreneurship should definitely check this out! The interview with Robert was such a pleasure. It

Out today at Nature Communications In collaboration with our awesome UB colleague, Sangwoo Shin, we report how ion gradients control the formation, localization, and transport of biomolecular condensates. nature.com/articles/s4146…