Nobuhiro Hiramoto
@hematologist_jp
General Hematologist.
ID: 1386674553766629376
26-04-2021 13:32:47
118 Tweet
95 Followers
68 Following
Thrilled to share our most recent Leukemia Journal “SETBP1 is dispensable for normal and malignant hematopoiesis”. In collaboration with outstanding Japanese researchers, we extensively examined the roles of endogenous SETBP1 in the hematopoietic system. rdcu.be/dg6Gh
Jordi Xiol PD-1 has single agent activity. Anti CD47 (magro) had no single agent activity in MDS. Drugs with no single agent activity rarely if ever improve outcomes in RCTs when used in combination
Dr Naval Daver, M.D. & I have signed the treaty of Kyoto to end all disagreements in the field & to reconcile all the differences in classification, risk stratification & response assessment between higher risk #MDSsm & #AMLsm
Enjoyed reading this analysis of HMA-VEN & IC in pt ≥60yo w/ newly-dx IDHm AML led by Shai Shimony Maximilian Stahl Rory M. Shallis, MD et al #leusm -151 pt (81 IC 70 HMA-VEN) -cCR rate 67% for both groups -2y OS 45% for cohort (51% for IC, 35% for HMA-VEN p=0.14) onlinelibrary.wiley.com/doi/full/10.10…
Wow, out just in time for your weekend reading-- our last four years labor of love "Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition"!! nature.com/articles/s4137… Congratulations to first author newly minted Dr. Sana Chaudhry! Sylvester Comprehensive Cancer Center 🧵