What happens when advanced tx don’t work in UC? Check it in @IBD360 bit.ly/4cByJx7 1. IBD market scan. 2. Advanced tx don’t work IRL in > 50% (Fig 1). 3. When this happens, costs go up (Fig 2). We need better meds.

Our 2025 APP IBD Preceptorship Program is accepting applications for new pediatric host sites to mentor future clinical leaders in Crohn’s disease and ulcerative colitis. Join this training program for NPs, CNSs, and PAs. Apply now: bit.ly/48nDNCE

When tx don’t work, IBD patients end up in ERs What does this mean? Check it out in Crohn's & Colitis 360: bit.ly/3zNW0x6 The cost of care goes way up (Table 1) Key problem – finding these patients and helping them in advance.

JAKs work in UC – real well Check it in IBDJournal & CC360. bit.ly/4c4TmBo RWE of TOF in UC 1. Refractory patients (Table 1) 2. AS and med refractory US (Fig 2) 3. Good efficacy in refractory pts (Fig 3).

Performing ileal pouch anal anastomosis surgery AFTER liver transplant may reduce the risk of pouchitis in IBD-PSC patients🧐 Read more at: doi.org/10.1093/crocol… Saqr Alsakarneh, MD, MSc Jana G Hashash, MD, MSc Francis (Frank) Farraye, MD, MSc

First it was 6 minutes, then it was 9, now it’s 15? 🧐 ⏰Every 1 minute ⬆️ in withdrawal time in colonoscopy in IBD pts = 4% ⬆️ in visible dysplasia detection Check it out at academic.oup.com/crohnscolitis3… Chandler McMillan Jill Gaidos, MD Badr Al-Bawardy

Largest population based study to examine the effects of cannabis in IBD 🌿 ⬆️ ED visits ⬆️ Hospitalizations ⬆️ Use of steroids and opioids 💊 🚫 IBD related surgery or mortality Penn State Division of GI and Hepatology academic.oup.com/ibdjournal/art…

Hot off the press! 🗞️ First consensus statement on screening and mgt of anxiety and depression in IBD 📋 Laurie Keefer, PhD Stephen Lupe academic.oup.com/ibdjournal/adv…

🤖 AI use in acute severe UC 🤖 Images of BMs for pts with ASUC were analyzed by validated AI and correlated with CRP💩 ⬆️ Stool fragmentation, Bristol score, mucus = ⬆️ CRP ⬇️ Consistency = ⬆️ CRP academic.oup.com/crohnscolitis3… Sarah Rotondo-Trivette, MD Gil Y. Melmed, MD, MS

How often during a colonoscopy in a patient w #CD could we have missed lesions that would have led to a change in therapy? I’ve wondered about this many times Virginia Solitano addresses it in her 📄 🔍 22.3% had lesions proximal to the TI 🔍 24.5% SB skip lesions in the ileum 🔍

Induction of Endoscopic Response, Remission, and Ulcer-Free Endoscopy With Upadacitinib Is Associated With Improved Clinical Outcomes and Quality of Life in Patients With Crohn’s Disease IBDJournal & CC360 Peter Bossuyt #upadacitinib #IBD academic.oup.com/ibdjournal/art…

Are you a #GIFellow interested in pursuing a career in IBD but on the fence about an extra year of fellowship? 🤓 Read more about pros/cons of #IBDFellowship here: academic.oup.com/crohnscolitis3… Katie Falloon Miguel Regueiro