hello world! new results (with jared toettcher): tinyurl.com/3595banh Stem cells can self-organize morphogenesis in vitro w/o spatial patterning cues. But how? We programmed cells to record their signaling histories to map symmetry breaking during gastruloid morphogenesis (1/n)

Our STEM CELL ZOO paper is out in Cell Stem Cell! By using in vitro differentiation of ES/iPS cells, we recapitulated the segmentation clocks of mouse, human, rabbit, cow, marmoset, and even rhinoceros🐁🧍‍♀️🐰🐄🐒🦏 They showed species-specific clock periods! dlvr.it/SqykTL

Have you ever wondered who organizes the organizer? Excited to share our latest discoveries about how a global application of retinoic acid (RA) can induce polarized neural tube organoids (NTOs). For more details, check out our pre-print below: biorxiv.org/content/10.110… 1/6

starry night Yokogawa Life Science Nikon Instruments

Great postdoc opportunity that gives you lots of freedom to explore your interests among multiple groups in Dresden. I can highly recommend as an alum. Happy to answer any questions!

If you are interetsed in a postdoc in Biological Physics or Quantitative Biology, check out our flagship Postoctoral Fellowships Physics of Life Dresden! - 4 years! - Independent postdoc (explore your ideas) - Many social benefits. - Mentorship plan. And much more 😃 Apply!

Very happy to share our manuscript on positional memory, in which we ask how axolotl cells 'know' which part of the limb to regenerate after injury. biorxiv.org/content/10.110… A joy to work with super team Sarah Plattner, Yuka Sugiura and Elly Tanaka Elly Tanaka IMP! 🧵1/14

bioRxiv is 10! Amazing to think how far we've come. Support from the scientific community has been incredible over the years - thanks so much to all involved 🙏 1/3

Can metabolic processes instruct cell fate decision making during embryonic development? In our new preprint, we show an important role of glycolytic activity for the development of endoderm and mesoderm through the regulation of Nodal and Wnt signalling. biorxiv.org/content/10.110…

Really excited about this deeply collaborative and interdisciplinary project! An opportunity to use next generation methods to solve old (unanswered) questions in #development and #transcription. Get in touch soon if you are interested and please RT!

I am delighted to share our paper “Modeling Post-Implantation Human Development to Yolk Sac Blood Emergence,” published nature – our model a.k.a. heX-Embryoids nature.com/articles/s4158…

Very happy to share a preprint of our work investigating how the embryonic brain expands and departs in morphology from the spinal cord early in development. Great to collaborate with Edouard Hannezo Shilei Xue FranzeLab 🇺🇦 and Alex Winkel on this. -> doi.org/10.1101/2024.0…

CSB students, staff and faculty gathered yesterday for a #ValentinesDay social hour, complete with chocolate covered strawberries and ping pong tournaments.

Yeah! Our protocol for segmentation, analysis and visualization of #volumeEM data is now published in Nature Protocols. Thank you to all colleagues, reviewers and to Rosy 🌻🌻🌻 for editing. Martin Weigert Paul Langerhans Institute Dresden - PLID Here is the link: rdcu.be/dzYGO

Very cool definition. I do agree

Attention organelle enthusiasts!! I am beyond thrilled to introduce Nellie: a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D/3D live-cell microscopy. paper: arxiv.org/abs/2403.13214 github: github.com/aelefebv/nellie 🧵1/N

Extremely happy to share the first manuscript of the lab! 🥳🥳🥳In this paper, we have looked at the coupling between delamination and differentiation at gastrulation. If you are interested in pluripotency, gastrulation, and mouse embryos keep reading! sciencedirect.com/science/articl…

1. My top imaging trick to trainees is that before they spend any time taking pictures of the data they just sit there for a while & look at the stuff. Like seriously, sit back, crank some tunes, get cozy & spend some quality time with your slides.

Now out! I'm beyond thrilled to share our method for dynamically measuring neurulation forces. We hope that our addition to the toolkit will push forward the quantification of living tissue mechanics. Elvassore Lab Gabe Galea Università di Padova Developmental Biology & Cancer Marie Skłodowska-Curie Actions nature.com/articles/s4156…

Dear Colleagues, We are recruiting an endowed assistant professor at the Laufer Center for Physical and Quantitative Biology laufercenter.org The job description is posted in apply.interfolio.com/150310 May I suggest you share this opportunity with colleagues? Kind regards,