BREAKING NEWS: The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”

Congratulations to Darrell Kotton who was recently awarded a $2.4 mil grant from the NIH NHLBI to study the mechanisms that initiate and perpetuate idiopathic pulmonary fibrosis! Read more in the press release here: bumc.bu.edu/busm/2020/12/1…

"...potentially translatable safe therapeutic intervention to harness liver regeneration via controlled expression of endogenous mitogens in vivo using lipid nanoparticle-complexed nucleoside-modified mRNA.." nature.com/articles/s4146…

In our recent paper, my lab used mRNA-LNP, the tool used to deliver the COVID-19 vaccine, to promote regeneration following acute and chronic liver injuries. mRNA-LNP as a safe therapeutic intervention for liver regeneration bionewscentral.com/mrna-lnp-as-a-…

Exciting new data from the Gouon-Evans lab at CReM using LNP-mRNA delivery platforms to promote regeneration in acute and chronic liver injury! Congrats to lead authors Fatima and Elissa Everton. Check it out here: nature.com/articles/s4146…

Great work from Elissa Everton, Anna Smith, and the rest of the team! Modified #mRNA to promote liver repair - what can’t mRNA do?

Check out the most recent Nature Communications publication from the Gouon-Evans lab CReM!

Sharing the first video from our inaugural virtual #CReMDance Film Festival. Director/producer/cinematography: Meenakshi Lakshminarayanan who is our amazing Administrative Director. #BearsBeetsBattlestarGalactica

Happy to share this week's video from our #CReMDance Film Festival. The visionary behind this film is Dar Heinze, a postdoc in the Gustavo Mostoslavsky lab. Apologies in advance that you will have this song stuck in your head for the rest of the week!

Thrilled to share our latest work using base-editing to correct the Z mutation in Alpha-1 antitrypsin deficiency #AATD in iPSC-derived hepatocytes, out now in Molecular Therapy pubmed.ncbi.nlm.nih.gov/34217893/ Here's a thread of what we found 👇

Well done Anna Smith from @EvansGouon Lab for being awarded second place at Russek Day BU GMS. Cell based therapy for liver disease coming soon, thanks to you Anna!

Bio-protocol #FactualFridays presents a new series highlighting Bio-protocol articles authored by Nobel laureates! We begin our series with #nobelprize2023 awardee in Physiology or Medicine, Dr. Drew Weissman at The Drew Weissman Lab #UPenn ▶️bio-protocol.org/en/bpdetail?id… #bioprotocol

Transient growth factor expression via mRNA in lipid nanoparticles promotes hepatocyte cell therapy to treat murine liver diseases biorxiv.org/cgi/content/sh… #biorxiv_cellbio