Cellecta, Inc.
@cellecta
Cellecta provides products & services for the discovery of therapeutic targets and specializes in pooled CRISPR & RNAi screening to identify cancer drug targets
ID: 218673086
http://www.cellecta.com 22-11-2010 23:41:51
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Many #CRISPR #globinopathy therapies target fetal globin. But delta globin is closer to adult globin *and* is expressed at low levels throughout life. ETH Entrepreneurship Pioneer Fellow Mandy Boontanrart developed #geneediting "fix" for the delta promoter! biorxiv.org/content/10.110…
We have dissected the mechanism of how EGFR regulates the immunosuppression status (more resistance to immunotherapy) of triple-negative IBC. We hope that this will be a game-changer treatment for patients with IBC. Published in Science Advances science.org/doi/10.1126/sc…
In this Primer, Erhard and Saliba et al. discuss metabolic labelling approaches and how to assess the temporal dynamics of transcriptional responses in different conditions @idoamitlab kathleenabadie Dölken Lab go.nature.com/3dzCh9C
A new review from Jennifer Doudna (Doudna Lab) & Joy Wang in Science Magazine takes us through the last ten years of #CRISPR – and what to expect in the next ten: scim.ag/1e0