Atherosclerotic plaque epigenetic aging, a new predictor of poor prognosis linked to patients with Diabetes and high BMI and linked to EndMT Hester den Ruijter Edmfn ahajrnls.org/44pJ0ZY

cool story! ⁦Steven Botts⁩ has an endothelial identity project that is on display now at #vasculardiscovery ⁦ATVB: An AHA Journal⁩ vascular discovery. We’re seeking a talented post-doc - join us and pursue the next chapters! ⁦Jason Fish⁩ ⁦Kathryn Howe⁩ ⁦University Health Network⁩

Excited to be a part of this work from Josh Wythe. 3D uCT of KRAS-driven brain AVMs reveals stereotyped locations that coincide with endogenous Kras. Human bAVMs show spatial restriction. MEK inhibitors in mice and paediatric patients impedes progression. biorxiv.org/content/10.110…

This innovative, four-year collaboration is a critical new step toward building a better understanding of the heart-brain connection and improving health outcomes for all Canadians. Learn about this groundbreaking research collaboration: bit.ly/3wxBEqS.

This program looks fantastic! Send your trainees to this meeting. It is a great opportunity to learn state-of-the-art approaches in vascular biology and to develop their network. At Stanford University from July 22-25. navbo.org/vasculata/ NAVBO

We are pleased to announce the promotion of seven of our faculty this year. Department Chair, Dr. Rita Kandel commented, "These individuals have all made outstanding contributions to various research and clinical areas". lmp.utoronto.ca/news/lmp-promo…

Special day ⁦Sneha Raju⁩ just defended a BRILLIANT PhD! Amazing to see how this journey has shaped your mind, your communication, and your scientific spirit. ⁦Jason Fish⁩ and ⁦Kathryn Howe⁩ are 2 very proud supervisors right now and always. Massive thanks ALL!

This looks great! A favourite topic of mine as well.

Register and take advantage of the SUPER Early Bird Discount (ends TODAY -June 30). Plan to attend Vascular Biology 2024 in California, October 20-24, 2024 at Asilomar Conference Grounds. Details & Registration: navbo.org/vb2024/

Just received the promotional posters for #VascularBiology2024 & figured I should spread the word on line too. Sessions on #malformations #microcirculation #metabolism #mechanotransduction etc And the one dear to my ❤️ and organized by Ying Zheng & I on #bioengineering

An international consortium of researchers led by University Health Network Krembil Brain Institute & University of Zurich build first-ever molecular atlas of the human brain’s vasculature, across early brain development, adulthood & disease. Read more in nature -> bit.ly/4cW2poc

I am very happy to share that my first-author paper from the PhD work is now published in Nature: nature.com/articles/s4158…

Excited to see this collaborative work published today. Led by Thomas Wälchli and Ivan Radovanovic UHN Research. Single-cell atlas of endothelial cells across human development, adulthood and disease (brain tumours and arteriovenous malformations). nature.com/articles/s4158…

I'm very excited to share our paper "Single-cell atlas of the human brain vasculature across development, adulthood and disease" - lnkd.in/dRjimb4u published in Nature! Further reading: - lnkd.in/dpMAbrFy (Nat Rev Neurosci) - lnkd.in/d42nGSBR (JCI Insight)

Congrats Dr. Cheng Michael Cheng on a successful PhD defense and thanks to Rod Russell for being an excellent external examiner and presenting his unpublished work on cell death pathways induced during viral infections! #liverlaughlove

🚀 Thrilled to share our new publication in Nature CVR! We revealed the crucial role of a newly described APOE+ valve interstitial cell subtype in human valve remodeling. Huge thanks to our amazing collaborators! 🙌 Jason Spence Ya-Wen Chen YutzeyLab Simon Miao

We are recruiting multiple graduate students to explore funded projects on how #Stemcell-derived LSECs gain and maintain their functions. Bring your #Cellculture #CRISPR #scRNAseq skills to fight #LiverDisease and #HemophiliaA as a #CellTherapist. ohri.ca/profile/bgage/…

Our study on in vivo functional maturation of hPSC-derived Kupffer cells is out today Cell Reports. cell.com/cell-reports/f…

Incredibly honoured to receive this award! This recognizes the hard work of my lab members, mentoring and support from colleagues, the fantastic collaborations that we have been involved with, and an outstanding research environment. UHN Research Department of Laboratory Medicine & Pathobiology Peter Munk Cardiac Centre

Now published in the Sept. 5 issue of Cell: A holistic view of the vascular endothelium as a systemically disseminated organ. Go to cell.com/cell/fulltext/… if you want to learn more about the beauty and importance of endothelial cells in health and disease.