Made it to the top! Waiting on Loren Walensky The Harvard/MIT MD-PhD Program

Out now in nature: former Whitehead Institute researchers Max Valenstein, MD, PhD and Kacper Rogala solve the 3D structure of GATOR2, a protein complex that plays a key role in regulating cell growth: wi.mit.edu/news/form-foll…

Excited and grateful to share this with the world! Our structure of the mysterious GATOR2 complex sheds light on the ways that mTORC1 receives and integrates nutrient signals. Thank you to everyone who contributed to this work! 🐊🐊

The GATOR2 protein complex senses leucine and arginine, keeping track of nutrient abundance in a cell’s environment. The newly resolved #cryoEM structure reveals that GATOR2 uses distinct surfaces to sense these two amino acids in parallel. Max Valenstein, MD, PhD ow.ly/Bb6i50JYBgk

You catch more flies with leucine! Congratulations to Xin Gu and team for revealing that nutrient sensing by mTORC1 influences dietary choices in Drosophila! Read it to see what the buzz is all about!🪰🍎 nature.com/articles/s4158…

The MGH IM Residents Stanbury program attracts and trains top physician-scientists. At this year's summer retreat, MassGeneral Medicine family member Rochelle Walensky, MD, MPH shared her insights on matters relevant to her tenure as CDC Director.

First days in the lab 2007

In honor of 25 years of mTOR we reorganized the lab antibody box... Is this still good? David M. Sabatini Max Valenstein, MD, PhD José Miguel Orozco Kendall

Relatable x.com/mattzap/status…