Sapkota Lab develops innovative proximity-inducing small molecule and demonstrates targeted dephosphorylation ppu.mrc.ac.uk/news/sapkota-l… iScience journal

Founder of the sustainability framework #LEAF wins prestigious EMBO award. The MRC PPU currently holds a Silver LEAF award and is working towards #GoldAward #Sustainability Medical Research Council

New discovery by Sapkota Lab and Barcelona Clinical Team sheds light on rare skin disorder mechanism ppu.mrc.ac.uk/news/new-disco… #palmoplantar #PalmoplantarKeratoderma #PPK

This was an excellent collaboration with the team at Hospital Universitari Vall d’Hebron and very grateful to have the opportunity to not only provide molecular insight into the novel FAM83G mutation but explore our interest in FAM83-CK1 biology with patient-derived cells! 🙂

Exciting opportunity to undertake research in Nazma Malik's new laboratory at the MRC Laboratory of Medical Sciences in the area of Metabolism in Immunity, Cancer and Ageing

Join us! Postdoctoral Research position available in the lab of Ralitsa Madsen Further information can be found here ppu.mrc.ac.uk/careers/recrui…

Opportunity for a postdoc to join Raja S. Nirujogi MRC PPU for a joint project with Prof Siddharthan Chandran / Dr Bhuvaneish T.Selvaraj Selvaraj at the UK DRI at Edinburgh! Develop blood-based biomarkers for MND/ALS using ultra-sensitive mass spec & proteogenomics 👉buff.ly/3WwbpKl

Our Annual Summer School closed with its symposium. Congrats to the poster prize winners: 🏅 Winners: Kodi Hunter (Manu De Rycker lab Drug Discovery Unit) & Gabriella Saksono (Ganley Lab MRC PPU) 👏 Runner up: Emmanuel Laditi (Li Kang UoD Medicine) Full story: buff.ly/4dkHo7d

Science Forum: Antibody characterization is critical to enhance reproducibility in biomedical research doi.org/10.7554/eLife.… eLife - the journal

Think you know how granzymes work? Think again! GzmA protects against intestinal Salmonella infection, but GzmB helps Salmonella, and perforin has no role at all. Read about this complex story of the battle between host and pathogen here tinyurl.com/2enehsx9 Tweetorial below

Newly published research from the Mahima Swamy lab reveals how intestinal immune cells combat Salmonella infection, using specialized killer molecules called Granzymes ppu.mrc.ac.uk/news/protectin… Mucosal Immunology

4 more days to apply 👇🏻 if you’re an interdisciplinary scientist keen to develop your career, this is for you! Come join us 🤓

Out Now! Updated story on #HRI kinase as a negative regulator of #PINK1 mitophagy. We now show that the small molecule ISR inhibitor #ISRIB boosts PINK1 activation. Collaboration with Ganley Lab Rousseau Lab MRC PPU & Glenn Masson Click here for paper shorturl.at/G0IzL

Fantastic to have led this interesting work on the regulation of PINK by ISR with Pawan, IlariaVolpi Miratul Muqit and see this online. Great teamwork and collaborators Léa Wilhelm Ganley Lab Glenn Masson Rousseau Lab MRC PPU. Please check it out!

Congratulations Rachel on securing this fellowship. Excited to see the new discoveries you will make. #ProudPI

Pleased to have contributed to this exciting new story on #Parkin activation from Atul Kumar Lab #Parkinson #mitophagy mechanisms Click to read paper here: elifesciences.org/articles/96699

Researchers leading groundbreaking cancer and Parkinson’s research have been given almost £30 million to bolster their vital work over the next five years. 👏 We are enormously grateful to Medical Research Council – UKRI for their generous support for MRC PPU. More: buff.ly/3XbPTuA

We’re delighted to announce a further £27.4m of funding over five years to support the MRC PPU to continue ground-breaking research into the mechanisms of diseases like Parkinson's, and the development of new treatments. More: orlo.uk/r4KNo

We are enormously grateful to the Medical Research Council (MRC)/UKRI for their generous long-term support - 34 years and counting - for our research Unit at the University of Dundee ppu.mrc.ac.uk/news/mrc-ppu-g… Medical Research Council UK Research and Innovation #Dundee