I am delighted to see that our work on using [3.1.1]propellane to derive meta-arene bioisosteres is accepted in nature nature.com/articles/s4158… Ed Anderson Group 🇺🇦 Duarte Group Brennan Group Schofield Group AbbVie Jeremy Nugent Bethany Shire Helena Pickford Alistair Sterling

Researchers at Oxford Chemistry, Raphael Reinbold and Schofield Group, report studies on resistance to the pioneer drug ivosidenib leading to identification of inhibitors retaining activity. go.nature.com/3R5bVdx

Day two of #DDC2022 has started with excellent scientific lectures by Prof. Dr. Christopher Schofield Schofield Group and Prof. Dr. Rolf Müller Antibiotikaforschung (inaktiv)! Thank You! 😊 🤩

In Situ Inhibitor Synthesis and Screening by Fluorescence Polarization: An Efficient Approach for Accelerating #DrugDiscovery (Zhang) Schofield Group #openaccess onlinelibrary.wiley.com/doi/10.1002/an…

‘Bicyclic boronate inhibitors’ is not a phrase you hear often... But they’re crucial in fighting antimicrobial resistance. And they’re a field where 🇬🇧 - 🇸🇮 researchers are collaborating, to great effect. Thank you @ARRS_rfo for an excellent day aimed at building more such links

At today’s launch for @ARRS_rfo’s UK-Slovenia Researcher Mobility Scheme, researchers working in 🇬🇧 and 🇸🇮 gathered to explore new projects and partnerships.

🩻🔬🦠🧫A case study: UK and Slovene researchers are together finding new ways to tackle the growing problem of antimicrobial resistance - and keep your antibiotics working. (Bicyclic boronate inhibitors! No 🚲 involved though…) #AMR

Metallo-β-lactamase-mediated antimicrobial resistance and progress in inhibitor discovery McNally lab group IMIBirmingham Schofield Group dlvr.it/SkGw1g

Congratulations Giorgia Fiorini!

After a long wait, extremely happy to see this work out nature.com/articles/s4155… WHATACOMPLEX! great collaboration with amazing group of people in Hiro Suga's lab Tokyo 東京大学 大学院理学系研究科 化学専攻　理学部化学科 Chris S lab Schofield Group and Akane Kawamura Newcastle University link here: rdcu.be/dcKJe

In JACS Au today! We show how D-NEMD simulations can be used to identify functionally relevant allosteric sites and communication networks in SARS-CoV-2 #Mpro, including those relevant to drug resistance pubs.acs.org/doi/10.1021/ja… #compchem. Congrats, Henry and everyone involved!

Answering questions about research & career journeys as part of our ⁦Ineos Oxford Institute for Antimicrobial Research⁩ ⁦Oxford Chemistry⁩ ⁦Schofield Group⁩ Bug Fight! Workshop⁩. Thank you ⁦Carterton CC⁩ for trialling this with us today. ⁦MPLSOxford⁩ ⁦⁦Oxford Undergraduate Admissions⁩

Delighted to share our new work in Nature Cancer in collaboration with Schofield Group led by Hannah Lawson & James Holt-Martyn. We found that HIF hydroxylases are potent therapeutic targets in AML. The ICR. nature.com/articles/s4301…. 1/4