Are you interested to learn & apply #DataAnalytics? I've got you covered! Accessible recorded lectures with linked #Python interactive #dashboards & well-documented demonstration workflows. I curate and share all my university #educational content to support anyone interested

Our latest: We explore how cells interpret morphogen gradients during development using optimal control theory A thread explaining some of the ideas 🧵 sciencedirect.com/science/articl… 1/12

I have created a website for my visuals of dynamical motifs! These provide a nice introduction to dynamical systems in the context of neuroscience. Also thank you to Dr. Paul Miller for giving me permission to animate his figures. mitchellslapik.github.io/dynamical_moti…

Polygraph: A Software Framework for the Systematic Assessment of Synthetic Regulatory DNA Elements biorxiv.org/content/10.110…

Inter-organ communication during tissue regeneration In this Review Fei Sun & Ken Poss draw on recent mechanistic studies across various species, tissues & injury contexts to explore the role organs distant from an injury play in regeneration: journals.biologists.com/dev/article/15…

Our approach to infer forces from 3D fluorescence microscopy is published in Nature Methods ! t.ly/_oaXt Congrats to all authors sacha rémi dumollard Alex McDougall Hervé Turlier Simply type pip install foambryo to try And stay tuned... CIRB_CdF CNRS Biologie

Can machine learning help to uncover physical laws of animal morphogenesis? Together with the Vitelli group we use light sheet movies to learn how the interplay of gene expression and cytoskeletal activity drives tissue flow. biorxiv.org/cgi/content/sh…

New genomes for Christmas :) Check out our new preprint, featuring the haplotype-phased S. mediterranea assembly, chromosome-scale assemblies of three additional Schmidteas, and the surprising discovery that flatworm genomes appear to evolve without syntenic constraints.

How similar are computational and biological systems? How can computer science get inspiration from biology? Here's a great @EMBOpress paper by UMD Department of Computer Science Saket Navlakha & Ziv Bar-Joseph on the convergence between biology and computer science: embopress.org/doi/pdf/10.103…

Our first paper is out in Cell! Led by Rohith Rajasekaran, we present a programmable reaction-diffusion system that generates synthetic protein waves, oscillations, and patterns for spatiotemporal circuit design and FM data-encoding in human cells. authors.elsevier.com/a/1iN8ZL7PXmeeN

Just posted a preprint on our new spatial genomic recording system, baseMEMOIR. biorxiv.org/content/10.110… Motivation: Cells divide, differentiate, and migrate to form exquisitely organized tissues. Reconstructing the dynamic histories of individual cells, including their lineage

A Perspective in Nature Aging discusses the Information Theory of Aging, which proposes that aging primarily stems from the loss of youthful epigenetic information that can be restored via epigenetic reprogramming to heal injury and reverse aging. 🔒 go.nature.com/3S3ApHD

We celebrate the 20th anniversary of our lab with a paper just out in the 50th anniversary special issue of Cell A great way to start 2024! A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma: Cell cell.com/cell/fulltext/…

Final version of this one is out: pubs.rsc.org/en/content/art… "Machine learning for hypothesis generation in biology and medicine: exploring the latent space of neuroscience and developmental bioelectricity" see explanation in this thread from preprint: x.com/drmichaellevin…

Thanks Müller Lab for the excellent perspective. Love the musical chord analogy.

Glad to see this work released👏👏! Congrats🎉🎉!! It's really fascinating to see how cell division can pass on the information a system needed for symmetry breaking!

Very insightful and constructive work!!! Congrats!! I love the way you draw and organize the figures, so pretty!

What is the origin of our body? Our paper Cell shows that when a human embryo is one day old and comprises just two cells, only one cell will create most of the fetus in addition to placenta, while the other cell will create placenta. cell.com/cell/fulltext/…

Using ancient DNA recovered from a fossil bone, researchers in Science Advances have reconstructed a complete genome of the little bush moa, an extinct species of flightless bird that once roamed the forested islands of New Zealand. scim.ag/75U

David Brückner Thomas Gregor William Bialek In many developmental systems, cells don’t read out pre-established gradients, but interact to self-organize shapes. How can we quantify the information in self-organized patterns? We recently proposed how to measure the total information in a pattern. x.com/d_brueckner/st…