Trained on 1.5 million WSIs from 100,000 patients, a pathology foundation model is shown to improve performance of specialized models in detection of rare cancers Paige Microsoft Research #DigitalPathology #FoundationModel nature.com/articles/s4159…

Have been waiting for this for a long time and finally I've made it to Assoc Prof! Thanks to all the people who make this possible. Special thanks to Duke-NUS Medical School who provided me the opportunity to grow and shine and putting such a nice ceremony to celebrate this milestone!

Parasite can deliver therapeutic proteins to the brain!

A microbial metabolite inhibits the HIF-2α-ceramide pathway to mediate the beneficial effects of time-restricted feeding on MASH dlvr.it/TBqqbH

In the latest issue! Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity dlvr.it/TBr1Kf

CCL19-producing fibroblasts promote tertiary lymphoid structure formation enhancing anti-tumor IgG response in colorectal cancer liver metastasis dlvr.it/TC0KQq

Great review on extracellular vesicles #EV

The role of macrophages in obesity and cancer.

Acute liver failure (ALF) is a life-threatening disorder. Although liver replacement is the best current therapy, artificial liver support systems may be beneficial to patients. A Seminar discusses the causes and management of ALF: hubs.li/Q02M079c0

In the latest issue! Pan-cancer single-cell dissection reveals phenotypically distinct B cell subtypes dlvr.it/TCL3wq

TREM2+ macrophages are functionally important not only for restricting MASH-fibrosis progression but also for effective regression of inflammation and fibrosis. pubmed.ncbi.nlm.nih.gov/39172787/

Our work on Gata4 regulation of CCL20 and immunosuppression in HCC is now published! Nurul Jannah Nasir

It's great to have #lablunch for a few #celebrations today: my #promotion, our #publication, in coming #baby from lab members, #welcome to new member and #farewell to another member starting his #bioinformatics master program overseas.

New Review - Hagstrom et al - Natural history and progression of metabolic dysfunction-associated steatotic liver disease thelancet.com/journals/langa… #LiverTwitter #MASLD @hanneshagstrom @patriknasr @yingshang1

Excited to see all the world leading experts in liver cancer at the upcoming #ilca24 at #Toronto. Hurry to register ASAP!

Nature research paper: A brain-to-gut signal controls intestinal fat absorption go.nature.com/4d1al7d

Future of #omics meeting. Hk/shenzhen. Growing community of #scrna #ncrna #spatialtranscriptomics #proteomics nice research environment in #bgi

Transfer of mitochondria via nanotubes from bone marrow stem cells to CD8+ T cells augments cellular metabolism, empowering engineered T cells and tumor-infiltrating lymphocytes to counteract exhaustion and fight tumors more effectively Cell cell.com/cell/fulltext/…

Response to checkpoint blockade depends on optimal splenic antigen levels, whereas increased antigen induces differentiation to circulatory T cells Science Immunology Stefani Spranger science.org/doi/10.1126/sc…

Assessing clonal changes in T cells over time following immunotherapy is a breeze with Cyclone dlvr.it/TDCj1J