Prof. Akiko Iwasaki
@virusesimmunity
We study antiviral immunity and viral disease pathogenesis. #COVID19 #longCOVID #vaccines @HHMINEWS @YaleIBIO @YaleMed @YaleCII President of @ImmunologyAAI
ID: 864560037821370369
https://medicine.yale.edu/lab/iwasaki/ 16-05-2017 19:15:50
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This is a cautionary tale of how anti-Spike antibody may make COVID disease worse. In this study, the authors show that anti-Spike IgG made SARS-CoV disease worse by switching macrophage from wound-healing to proinflammatory phenotype. A thread (1/n) insight.jci.org/articles/view/…