.Yi Jin Manchester Institute of Biotechnology reveal overlooked conformational changes of phosphorylated Ras using BeF3-complexes by X-ray crystallography and 19F NMR, providing new mechanistic and conformational insights into Ras dynamics regulation. nature.com/articles/s4200…

It is another example to show GDP+BeF3- complex is a better mimic than GMPPNP, GMPPCP, and GTPgS for studying Ras and other small GTPases #QMMM. More importantly, it can be studied by #19FNMR

🎉 Celebrating #YearOfTheDragon🐲 with our 🇬🇧🇨🇳 The University of Manchester Friendship Programme students and friends from Manchester Museum & @ConfuciusMCR. ✨ The event started with a stunning Lion Dance, followed by music performances, bracelet-making, calligraphy, origami, and Taichi workshops.🧧

Poster abstract deadline approaching…

Just published: The importance of 7-deazaguanine modifications in the molecular biology of DNA and tRNA. Roles in translation, cellular stress resistance, self-nonself discrimination, host evasion defenses and natural products are discussed. Have a read: journals.asm.org/doi/10.1128/mm…

OUT NOW: New study by Henri Voedts Constantin Anoyatis and Michel Arthur digging into the mechanisms of (p)ppGpp-dependent beta-lactam resistance in E. coli 🦠💊 nature.com/articles/s4156…

A potential vaccine candidate for tuberculosis, supported by Wellcome and Gates Foundation, has started its Phase 3 clinical trial in South Africa. If shown to be well-tolerated and effective, the vaccine could become the first tuberculosis vaccine in over a century.

Metal fluorides - multi-functional tools for the study of phosphoryl transfer enzymes biorxiv.org/cgi/content/sh… #biorxiv_molbio

Metal fluorides are super useful in structural biology! Pleased to share our 'cook book' bioRxiv on the best ways to prepare these complexes for X-ray, #cryoEM, SAXS and NMR studies and a brand new metal fluoride - Scandium tetrafluoride biorxiv.org/content/10.110…

Thank you NVIDIA AI Technology Center (NVAITC - APS) for welcoming NUS SynCTI with the Enzyme Function Initiative Team to discuss how AI could potentially help in developing approaches to identify new enzymatic capabilities

Merci pour nos discussions amicales et franches, essentielles pour nos pays et pour l'équilibre du monde. À bientôt ! 感谢你们进行友好坦诚的交流，这对我们两国和世界的平衡都至关重要。再见

Thank you Josie Parker for the invitation to deliver a seminar at Cardiff University Cardiff University School of Biosciences. It was great to chat about new projects with people that have such broad interests and experiences.

...not to forget the sulfosugar crowd - congratulations on a well-deserved Horizon Prize Yi Jin Ethan Goddard-Borger ProfG Nichollas Scott, and all the others! #glycotime

I am very proud to be part of this international collaboration since my postdoc time at YSBL initiated by SJ Williams ProfG Ethan Goddard-Borger that has just been awarded the Horizon #RSCPrizes Royal Society of Chemistry! Now Yi Jin and Field Lab have joined forces from Manchester Institute of Biotechnology too.

#medchem #chembio #naturalproducts #RNA #antibiotics, etc. Looking for your first independent position or seeking change? Look no further. Come to be my colleague Wertheim UF Scripps UF Pharmacy in beautiful Jupiter, FL. Open rank faculty position. apply.interfolio.com/148891

Check out this issue of Current Opinion in Chemical Biology focused on #metabolomics. Edited by James McCullagh and Hector Keun . Some great stuff in there. 😉 sciencedirect.com/special-issue/…

What a great paper. Check out the work from Shahriar Mobashery's lab and cols. on restoring susceptibility to B-lactam antibiotics in S. aureus with a small molecule. nature.com/articles/s4158…

I’ll be at #ACSFall2024 . If you are in attendance and interested in joining our team come and find me. 2 vacancies closing soon! gibsongroupresearch.com/join-us/