Check out a new stats tool for dms by brilliant Jingyou Rao that integrates position to improve power. This work and our many other projects with Harold Pimentel was catalyzed when we met at a fantastic HHMI meeting! Rosace is transforming our analysis and so can it yours!

Come check out Jingyou Rao, Riley, and chris macdonald @[email protected]' work, Rosace! They describe a new statistical framework for handling deep mutational scanning data from growth-based screens

Join @Willowcoyote UC San Francisco & Raehoon Jeong #Harvardmed for the next Variants Effects Seminar Series, Tuesday Nov 7, 9 to 10 am (PST). Details: varianteffect.org/seminar-series #FunctionalGenomics #MutationalScanning #PharmacoGenomics #RegulatoryVariants #seminar

I passed my OQE today!!! Finally become a PhD candidate. Thanks a lot to my awesome committee and these friendly 🦭🪽🐬for listening to my practice talk again and again this weekend.

New paper by Nathan LaPierre and Harold Pimentel on the importance of accounting for isoforms when performing eQTL studies with #RNAseq. 🧬 Isoform-aware methods have greater power than gene-level methods 🧬 Not accounting for isoforms can inflate false discoveries journals.plos.org/ploscompbiol/a…

Our paper is finally out in it's final form!

this semester (spring 2024), i created and taught a new introductory course on causal inference in machine learning, aimed at msc and phd students in cs and ds. the whole material was created from scratch, including the lecture note and lab materials; docs.google.com/document/d/1qN… 1/4

Oh. Thank you. Hope everyone enjoyed my talk.

Post review Rosace paper is out! Big thanks to the reviewers who helped us improve the benchmarks, refs, and language of the paper. DMS is a new area for us so it was especially helpful. First of many DMS papers to come! Congrats and great work, Jingyou Rao x.com/JingyouR/statu…

I am a bit late to the party, but I am very excited to announce that I will be joining UCLA CS as an assistant professor starting January 2025 🎉 I will be recruiting students for the Fall of 2025. If you want to work on systems/compilers/PL apply to UCLA and email me :)

Coming up next month! 📌🗓️ Jingyou Rao Ayesha Muhammad @[email protected] varianteffect.org/seminar-series

If you want to hear about what we’ve been working on (mostly unpublished)! If you like biophysics, genetic variants, membrane proteins, or high throughput approaches check it out! Was an awesome meeting that brought together scientists with beautifully distinct interests!

Mutations in the kinase domain of RTKs like MET can drive disease. Small molecule inhibitors target these mutations, but acquired resistance poses a challenge. In our latest preprint, we've extended our previous 🧬DMS of MET to study this exact problem. doi.org/10.1101/2024.0…

24 DMS screens on MET kinase domain! This is a tremendous amount of work!

We’re extremely excited to announce the NeurIPS Workshop on Bayesian Decision-making and Uncertainty: from probabilistic and spatiotemporal modeling to sequential experiment design! This will take place at NeurIPS 2024, in Vancouver, BC, Canada, either on December 14th or 15th.

Are you looking for an inference algorithm that supports your discrete-continuous probabilistic program? Look no further! We have developed a new probabilistic programming language (PPL) called HyBit that provides scalable support for discrete-continuous probabilistic programs.