Clinical decision support (CDS) for Familial Hypercholesterolemia (LDL>190), increased statin usage and lowered LDL-C levels. A pre-post implementation study led by Hana Bangash and presented American College of Cardiology today. Mayo Clinic CV #cardiotwitter

Come see Alborz Sherafati🇺🇦 present his poster on Association of PRS for CHD with Angiographic CAD Severity at 9:45 in Hall F, Theater 7 #ACC23

Alborz Sherafati🇺🇦 presents today American College of Cardiology A polygenic risk score for CHD is associated with angiographic CAD severity. Work led by Alborz Sherafati🇺🇦 & Kristjan Norland Mayo Clinic CV

Our new report says that researchers should rethink how race, ethnicity, and ancestry labels are used in #genomics and #genetics research. The report provides guidance to help researchers choose appropriate population descriptors for their studies. Read: ow.ly/wjzp50NhWJ0

Celebrating first day spring and #persian #new_year with Iftikhar J. Kullo and old friends Mayo Clinic Kullo Laboratory ! A great presentation by Alborz Sherafati🇺🇦 about the #history and #traditions of #Nowruz Hana Bangash Johanna Smith Mohammadreza Naderian Alexandra Miller Marwan Hamed

Happy Nowruz, the beginning of spring, and the Persian new year, from Mayo Clinic Kullo Laboratory. 🍀🌷🏡 🎉🎊

Excited to share this review with you all 😊 pubmed.ncbi.nlm.nih.gov/37223852/ #ASCVD #PRS

We'll miss you so much❤️

📣Our study exploring clinician perspectives on CDS for FH out now! 🔸Developed EHR-based CDS w/ clinician feedback 🔺clinicians agreed CDS good option for FH identification 🔺agreed it would improve early diagnosis of FH Iftikhar J. Kullo 📄 here shorturl.at/cCN59

Multi-ancestry PRSchd developed from diverse large multi-ancestry genome-wide meta-analysis sum stats improved single ancestry PRS but limited in AFR & HIS predictive performance- suggests need for incr representation at each stage of PRS development medrxiv.org/content/10.110…

🫀 Thrilled and honored to present at #AHA2023: 🧬Our recent work Mayo Clinic Kullo Laboratory, on the role of clonal hematopoiesis of indeterminate potential (CHIP) in cardiovascular diseases. 🔹 Immense gratitude to all who've supported me on this incredible journey!

It's conference season! Had an amazing time presenting about a multi-ancestry PRS at the CHARGE Conference this month. Mayo Clinic Kullo Laboratory

Greetings from the PRIMED Consortium PRIMED Consortium meeting in Arlington, VA!

The #gnomAD team is proud to announce the release of gnomAD v4! The v4 dataset includes 730,947 exomes & 76,215 genomes, which is ~5x larger than the v2 & v3 releases combined, & includes nearly 120K indivs of non-European genetic ancestry broad.io/gnomad_v4 #ASHG23 (1/11)

First day of AHA ended with A LOT to take in! I was honored to elaborate more on our published abstract on Lp(a) testing in clinical practice! Day 2, here we go! #AHA23 AHA Science Mayo Clinic CV Mayo Clinic Mayo Clinic Kullo Laboratory

1/2 #SDOH & Polygenic risk in AoU Kristjan Norland demonstrates that #SDOH account for increased CHD risk associated with self reporting as black, highlighting race as a social construct & supporting its replacement in risk equations with #SDOH preprint tinyurl.com/yaej5t5c

Thank you Circulation: Genomic and Precision Medicine for summarizing our article so well! Continuing to work toward lessening disparities in PRS for CHD 🧬 #multiancestry #prs #CHD

📢 🎉 A total of 21 @PRSDiversity Consortium publications have contributed to the PGS Catalog, now linked from our publications page and detailed in a new report with information on traits and ancestry groups, primedconsortium.org/publications/p…

Delighted to share our work demonstrating that PRS and clinical risk factors should be jointly considered towards personalized medicine. Honored and grateful to be guided by my great mentor Pradeep Natarajan and to work with an awesome team!

Please join us for NHLBI's 2-day virtual workshop “Return of Individual Research Results to Participants in Observational Cohort Studies” June 26-27.   Focuses on incidental genomic results Link for the agenda & registration below tinyurl.com/tru8es3t NIH NHLBI NHGRI