Out in Molecular Biology and Evolution: Physical constraints on epistasis. w/ Kabir Husain academic.oup.com/mbe/article-ab… What are the mechanistic constraints on epistasis (non-additive effect of mutations) in complex systems like proteins , regulatory networks? We find a broadly applicable constraint.

Join Simon Freedman @Madhav_science and I this Friday Mar 11 at 12:30pm CST for a talk and discussion by Prof. Eleni Katifori of Penn Physics & Astro on optimal trade-offs in biological flow networks! Sign-up details here karnagowda.github.io/biotheory/, or reply if you'd like me to send you a Zoom link.

If you're at #apsmarch, drop by my talk at 4, W-178A, session W05 (3 to 6pm, chaired by Daniel Weissman and Simone Bianco)! Also at youtu.be/snl8tg_yKZo We did Luria-Delbruck in eye-bleeding-throughput to learn something about standing genetic variation and evolvability. APS-DBIO

Now on bioRxiv, insights into architecture of biological oscillator from awesome PhD student Chaitra. We compare biosynthetic cost needed to suppress phase drift across TTFL circuits. Key determinant is which reaction steps are under regulation. biorxiv.org/content/10.110…

Beautiful experimental work from fellow postdoc in Seppe Kuehn Lab Kaumudi Prabhakara disentangling biotic and abiotic factors driving community assembly in phototroph-heterotroph systems! biorxiv.org/content/10.110…

We are organizing a BPS Virtual Networking Event: “Beginner Scientists at the Interface of Physics and Biology”, on September 15th from 9 am-1 pm (EST). Do join us and spread the word! Register here: biophysics.org/upcoming-netwo…

Our reviewed preprint on centrosome size control, led by deb sankar, is now online in eLife - the journal: doi.org/10.7554/eLife.… #TheoryInBiology

Interested in #Biophysics but unsure if you want to do a PhD? Apply to our new #MRes on #Computational Cell Biophysics. Please RT. #interdisciplinary #science #masters UCL UCL IPLS

One month to go until the London Quantitative Immunology Day on March 14th! Submit your abstract in the next two weeks to be considered for a contributed talk 👉 qimmuno.com/ldnday/

If you are in London tomorrow (March 13th) and fancy hearing about self-organisation in nonequilibrium, catalytically-active systems, you can catch me at 3pm at Imperial College! imperial.ac.uk/events/174858/…

Two postdoc positions in my group in Mathematical Biology Where: UCL Maths in London When: 1st September 2024 to 30th March 2026 What: Cell-based and/or continuum modelling of cell populations such as biofilms and swarms Apply: ucl.ac.uk/work-at-ucl/se… Deadline: 9th May

📢 Save the date for the next London Mathematical Biology Conference, happening 9-10/9/24 The Crick. Registration opens soon with many opportunities for contributed talks and abstracts. Spread the word!

**Recruiting two experimental Post Docs** We are recruiting postdocs to work on NSF and NIH-funded projects to build a quantitative, predictive, understanding of microbial communities from the lab to the field. kuehnlab.org

Out today after peer review: cell.com/cell/fulltext/… Congratulations Juan Díaz-Colunga Djordje Bajić Jean Vila & Abby Skwara

Out now - a long simmering project: A minimal scenario for the origin of non-equilibrium order. arxiv.org/abs/2405.10911 Led by Riccardo Ravasio Riccardo Ravasio and Kabir Husain Kabir Husain (now at UCL); + fun collab with Constantine Evans, Rob Phillips, Jack Szostak Szostak Lab

📢Don't miss our IPLS Seminar TOMORROW at 2pm UCL Laboratory for Molecular Cell Biology by Dr. Akshit Goyal Akshit Goyal from ICTS. ucl.ac.uk/physics-living…

A fantastic opportunity in a first-rate group!