🚨🚨 PAPER ALERT🚨🚨 Happy and proud to be part of this! Thank you, Lars Lau Raket, for bringing this work to fruition!

Now the proofread version of our paper is available online. It is among the handful of papers that I am most proud of having contributed to! I think it really shows that it is just a matter of time until plasma ptau217 will revolutionize the diagnostic work-up of AD globally.

What if disease-modifying therapies for #Alzheimers were evaluated by "time saved" rather than slowed rates of cognitive decline? Suzanne Hendrix Pentara, Lars Lau Raket, Geert Molenberghs KU Leuven, John Harrison & Ron Petersen, M.D. nature.com/articles/d4158…

How do we effectively measure disease modifying effects in progressive diseases like Alzheimer's? We are going to need a lot more work rethinking along these lines for measuring the effects of #longevity interventions nature.com/articles/d4158… highlights great work from medical

Would you believe me if I told you that a single variant in a non-coding RNA explains ~0.5% of all undiagnosed individuals with neurodevelopmental disorders (NDD) in Genomics England ??? I didn’t initially either, but here is the story of RNU4-2 🧵1/9

I am very excited to be taking on the role of chair of the ISTAART Design and Data Analytics PIA. Looking forward to working with this all-star executive committee, all of the members, and the amazing Alzheimer’s Association staff! 🧠📈💥

Harmonizing tau PET in Alzheimer’s disease: The CenTauR scale and the joint propagation model A first step towards a Centiloid equivalent for Tau PET. Great to see this published; I really enjoyed the discussions with the Working Group (and look forward to the next steps).

🚨🚨 Paper alert 🚨 🚨 I am honored to have been part of this article led by Lars Lau Raket. The article provides very important estimations of scenarios for the long-term effect of amyloid-targeting therapies! Also, with Michael Schöll Alexis Moscoso Rial alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

Emma Coomans just presented our large-scale tau PET study (>11,000 participants from 41 cohorts) providing robust prevalence estimates of tau PET-positivity as a function of age, amyloid, sex and APOE. #AAIC24 Many thanks to all our collaborators worldwide (way too many to tag)!

A friendly reminder that our ISTAART Design and Data Analytics PIA All Member Meeting is happening tomorrow (Tuesday 09/10) at 2 p.m. CT! Join us if you can 😎 Lars Lau Raket Ana Capuano Mike Malek-Ahmadi Natalia Goncalves Jet M.J. Vonk Nicolás