Augmented Memory: Sample-Efficient Generative Molecular Design with Reinforcement Learning By Jeff Guo & Philippe Schwaller (he/him) EPFL Read the paper 👉 go.acs.org/ax6

Thanks to TÜV SÜD the thermal safety analysis (DSC) of our new class of reagents -the Cyclopropenyl Benziodoxoles (CpBx)- is now finished and available on our website. Have a look if you want to use these new reagents! epfl.ch/labs/lcso/rese…

The #LCSOSynthesisProblem is back! Can you predict the outcome of these radical cyclizations? This week Najung Lee challenged us with the synthesis of (−)-Phaeocaulisin A by Procter Group in J. Am. Chem. Soc.. Take a look: epfl.ch/labs/lcso/wp-c… Original paper: doi.org/10.1021/jacs.2…

Very important work on the safety profile of Benziodoxol(on)e reagents completing our own work in the area by Obermüller, Mario Waser and co-workers! pubs.acs.org/doi/full/10.10…

🔥The front cover of issue 17 Green Chemistry highlights our study integrating mass- and energy-based metrics with life cycle impacts for sustainable chemicals manufacture #Sustainability NCCR Catalysis 🙏💚👇 pubs.rsc.org/en/content/art…

Happy to see our work on C-H azidation together with Zhu Group on top of the list of most accessed articles HelvChimActa in July 2024 (also there great contributions from The Matile Group 𝙺𝚊𝚛𝚕 𝙶𝚊𝚍𝚎𝚖𝚊𝚗𝚗 Carlos Vila Descals Prof Hevia 🇺🇦 Fabian von Rohr ... onlinelibrary.wiley.com/page/journal/1…

160.1 This week starts with a De Mayo type reaction of 1,3-dicarbonyls with BCB to give cyclobutanes after a retro-aldol reported by Sanzhong Luo and co-workers in Tsinghua University in Chemistry …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ch…

Congrats to Xingyu Xingyu Liu 刘星宇 for wining a runner-up oral presentation award at the Peptide Therapeutics Forum 2024 of Swiss Chemical Society with the support of HelvChimActa (photo from Swiss Chemical Society )

Can you complete the forward synthesis of (+)-Randainin D without seeing its structure? On the last #LCSOSynthesisProblem Christine challenged us with its synthesis by Baudoin Research Group in J. Am. Chem. Soc.. Take a look: epfl.ch/labs/lcso/wp-c… Original paper: doi.org/10.1021/jacs.4…

📢 #Call for SNSF Swiss Postdoctoral Fellowships 2024 This highly competitive call is aimed at researchers who wish to obtain a position in a non-profit research institution in Switzerland for a period of 12 to 24 months. 🗓️Deadline: 2 December 2024 sohub.io/6afa

Welcome to Jozef 🇸🇰 Jozef Kristek who joined LCSO as a visiting PhD student from the Pospisil lab. Best of luck!

The fall meeting #fm24 of the Swiss Chemical Society has been opened by Ali Coskun UnifrChemistry and rector of Uni Fribourg Katharina M. Fromm. We Are looking forward to a day of exiting chemistry

Athina Anastasaki D-MAVT, ETH Zurich gives the first lecture, the Werner Prize Lecture 2024, ‘Monomers from Polymer’ at #fm24 Swiss Chemical Society UnifrChemistry

Now it is the turn of Pierre Pierre Palamini to present his work at the Fall meeting Swiss Chemical Society

join us in Freiburg!! Tenure-Track Professorship for Theoretical Chemistry and Chemical Data Science RT appreciated uni-freiburg.de/en/job/0000392…

Ali Coskun gives the green and sustainable chemistry Award lecture 2023 #fm24 Swiss Chemical Society UnifrChemistry with the title ‘Porous Materials for Energy and Environmental Applications’. Congratulations

161.1 Only three this week: First a three-component reaction of alkynes, imines and cyclopropanes to give azepines reported by Sugimoto, Matsuya and co-workers from the University of Toyama in Adv. Synth. & Catal. onlinelibrary.wiley.com/doi/10.1002/ad…

We have now added the DSC stability data of benziodoxole-type reagents reported by Obermüller, Waser and co-workers in OPRD: pubs.acs.org/doi/10.1021/ac… In the database on our website: epfl.ch/labs/lcso/rese… The data of more than 40 compounds is now available!

And some fantastic news to end the week. At long last our work on BCBs is out in ACS Catalysis (link below). What started as an idea on an envelope over 4 years ago and then a "quick project to start your PhD" for Maxim ended up filling almost all of it.