Simon Little
@littleneuro
Neurologist & Neuroscientist interested in Adaptive Brain Stimulation, Movement, Mood, Motivation, Sleep, Self Regulation, Psychology and Dadding!
ID: 985521432674390016
https://littlelab.ucsf.edu/ 15-04-2018 14:13:14
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Excited to share this paper using new neurotech and explainable AI to advance DBS for treatment resistant #depression (TRD). Team effort including Helen Mayberg, MD, Sankar Alagapan and Patricio Riva-Posse. Summary thread! go.nature.com/48lmlzC @nature PC: Mike Halerz
Super happy to share some work by an awesome team led by Fahim Anjum investigating NREM sleep dysfunction in PD. Turns out that beta burst aren’t just naughty in the daytime… doi.org/10.1038/s41467…
There are 17 DBS and neuromodulation articles now published in Volume IV DBS Think Tank Frontiers - Neuroscience and the editorial is 'fresh' out this week and led by Kara Johnson, PhD The DBS Think Tank Proceedings led Joshua Wong also out. Read about: 1- Improving clinical practice and
Our study on reward and effort signals in PFC theta and basal ganglia beta is now out in PNASNews! Big thanks to the team (esp Coralie de Hemptinne and Simon Little), reviewers, and patients. pnas.org/doi/10.1073/pn… Data: osf.io/jq6z4/ Code: github.com/hoycw/PRJ_OFC_…
So proud of our 3 female first co-authors who led this project Carina Oehrn, Stephanie Cernera & Lauren H Hammer along with friend and co-senior author Philip Starr. Adaptive DBS for Parkinson's is out of the lab and into the real-world!
Why is DBS still a 'black box' to many folks with Parkinson's and beyond? Great pic from National Academy of Medicine National Academy of Sciences by Lauren Hammer who won 2023 DBS Rising Star Challenge. Free download of the proceedings. Exploring the Adoption of Implantable Brain Stimulation into Standard
Happy to share this preprint completed with Tanner Dixon and colleagues! Why try and smooth over and ignore movement in adaptive DBS when you can target it directly? All completed remotely in our patients home with a fully automated end-to-end programming pipeline…
1 million Americans have Parkinson’s disease. UCSF researchers are developing a new treatment, adaptive deep brain stimulation, that tunes into a patient’s brain signals and adjusts therapy as PD symptoms rise and fall. tiny.ucsf.edu/UFW7rX Simon Little UCSF Neurosurgery