Excited to share our new paper identifying Pim-1 kinase as a central mediator of senescent fibroblasts secretome. NF-kB, in all its complexity, needs further investigation in the settings of senescence and lung fibrosis. ⁦⁦⁩ journals.physiology.org/doi/abs/10.115…

Thanks to our awesome collaborative team at Mayo Clinic, including frailucopf.eth, Kevin Pavelko, Cori Fain, @kayasoufi, Aaron Johnson

The functions of oligodendrocyte precursor cells (OPCs) are not limited to oligodendrogenesis: OPCs engulf synapses during circuit remodeling in mice. nature.com/articles/s4159…

The Microglia Bible. What an amazing resource for the field. Thanks to all those who contributed. Neuron cell.com/neuron/fulltex…

Agree, such an awesome session! Thanks @dantyrr birgit schilling Matt Yousefzadeh Xu Zhang for fantastic talks! Thanks Rozalyn Anderson for outstanding leadership! #GSA2022 The National Institute on Aging (NIA)

Thanks for SenNet Consortium for a fantastic meeting!

Welcome to try our new tool: Single-cell Mayo Map (scMayoMap): an easy-to-use tool for cell type annotation in single-cell RNA-sequencing data analysis biorxiv.org/content/10.110…

Senescence and Inflammation: Summary of a Gerontological Society of America and National Institute on Aging-Sponsored Symposium Xu Zhang, @dantyrr, Tamara Alliston, birgit schilling, Matt Yousefzadeh, Marissa Schafer | UCSF Bakar Aging Research Institute UAB Pathology doi.org/10.1093/gerona…

Check our our new paper discussing brain TRM responses in health, acutely after neurological insults, and long after clearance of brain infection, and during antigen specific reactivation. sciencedirect.com/science/articl…

Congratulations to our awesome trainee Paul Timothy Gomez for winning an #AGE2023 poster pitch award! Great work Paul!

Jazzed to share Dr. Sarah Jachim's PhD research on the interplay between cellular #senescence and circadian dysregulation. New insights and approaches thanks to A. Matveyenko, @PassosLab, Jen Westendorf, T. Ordog, and outstanding collaborators Mayo Clinic aging-us.com/article/205112…

Excited to share our preprint demonstrating #senescent and disease-associated microglia are modifiable features of aged brain white matter Mayo Clinic Buck Institute SenNet Consortium The National Institute on Aging (NIA) dx.doi.org/10.21203/rs.3.…

Functional ultrasound is AMAZING.

Looks like an incredibly useful resource - well done João Pedro de Magalhães Cyril Lagger !

Spatial mapping of aged white matter, brain cell senescence, organ cross-talk and circulating biomarkers linked to brain dysfunction, and so much more! Come check out new research from the Schafer Lab at #SfN2023

Molecularly defined and spatially resolved cell atlas of the whole mouse brain nature nature.com/articles/s4158…

Check out our News & Views on an intriguing study by the Brunet Lab demonstrating partial reprogramming of the aged mouse brain. Kudos to Niels on this nice summary! nature.com/articles/s4358…

Great turnout and discussions at the 5th Annual Midwest Aging Consortium meeting in Columbus. Special thanks to all other co-organizers and funding agencies that made it happen. Looking forward to next year’s meeting at Mayo Clinic! MoraRojasAgingLab MidwestAgingConsortium

Now Online SenNet recommendations for detecting senescent cells in different tissues dlvr.it/T7n0tV

Researchers mapped 1.65M cells from 437 aging brains identifying paths of cellular change in aging brains, one leading to #Alzheimers and other to alternative form of #brainaging. Study in nature is foundational for personalized therapeutics for AD. nature.com/articles/s4158…