Mitchell O'Connell
@mitchellrayoco1
Assistant Professor, Biochemistry and Biophysics, @urochestermed. RNA-targeting CRISPR / RNA acetylation. An Aussie in 'the land of the free'. Music Nerd.
ID: 4443610175
http://urmc.rochester.edu/labs/oconnell-lab 11-12-2015 02:03:51
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Really great collaboration with Mitchell O'Connell and his student Adrian Molina , resulting in the development of new and more specific #crispr Cas13a systems !!
Our study on #RNA mediated allostery in #CRISPR-Cas13a paves the way for the development of new variants increasing the system specificity . Many thanks to Mitchell O'Connell and Adrian Molina for collaborating with us on this exciting project biorxiv.org/content/10.110…
Cheers to RNA biologist Lynne Maquat for officially receiving the Gruber Genetics Prize International Congress of Genetics 2023 in Australia for her work on nonsense-mediated mRNA decay. Proud to have you represent University of Rochester on an international stage! #URochesterResearch Maquat Lab urmc.info/15L
Excited for this! Adrian Molina has built an impressive body of work that we're all really proud of!
Congrats to Adrian Molina on hitting his thesis defense out of the park yesterday. Very proud PI. We will miss you but excited for what is next!
Now online: Antiviral type III CRISPR signalling via conjugation of ATP and SAM. Fantastic work by Haotian Chi and colleagues. nature.com/articles/s4158…
Now Nucleic Acids Res our two back-to-back papers with Mitchell O'Connell lab! Our #chemcomp paper unravels the #RNA-mediated allosteric regulation in #CRISPR-Cas13a and discloses functional mutations. academic.oup.com/nar/advance-ar… Souvik Sinha Pablo Arantes - @pabloarantes.bsky.social Adrian Molina & Amun Patel
The first FDA approval for CRISPR! A historic milestone! Thanks URochester SMD for getting a chance on riff on about this special occasion (unrehearsed and unscripted as you might be able to tell!). #URochesterResearch
Big congratulations to Adrian Molina graduating with his PhD, not to mention all the accolades along the way including the Leadership Award for Excellence in Equity and Inclusion bestowed at graduation. We're all very proud of all your accomplishments and we're gonna miss you!
Excited about phage functional genomics, phage engineering, & microbiome editing? The Cress Lab UC Berkeley Innovative Genomics Institute is hiring postdocs in these areas! Come chat w/ me Viruses of Microbes 2024 & don't miss my presentation w/ Ben Adler in the SynBio session Fri @ 11:20am. Retweets appreciated!