New review to read: DOI: 10.1146/annurev-biochem-052621-092014

Read our new study: nature.com/articles/s4225… Treatment of obese mice with small molecule inhibitors of mtDNA transcription (IMTs) leads to marked beneficial metabolic effects. The weight is normalized, the fat deposition in liver disappears and glucose homeostasis is normalized.

Research reveals how mitochondria and the cell nucleus coordinate to create proteins

Together with Jodi Nunnari we joined our knowledge on mitochondrial biology and medicine to this review now out in Cell. cell.com/cell/fulltext/…

Some of the highest expressed genes in our genomes are encoded by mitochondrial DNA. To understand how and why, we developed new methods that uncover the many quirks of mtDNA expression. Find out what we learned in our recent review by Erik McShane and me. academic.oup.com/hmg/article/33…

Wishing Bob and Zosia a happy retirement. The mitochondrial community if going to miss you!!!

Thank you to everyone that joined last week's EMBO meeting on mitochondrial gene maintenance and expression - for sharing your data and for all of the great discussions. We hope you enjoyed it as much as we did!

Thrilled to announce that our project has been published in Cell. In this work, we link mitochondrial dynamics to mitochondrial quality control and mtDNA maintenance by characterizing the molecular function of MTFP1. Please DM; happy to discuss! cell.com/cell/fulltext/…

Unique architectural features of mammalian mitochondrial protein synthesis 30-day free access to our new review at: authors.elsevier.com/a/1jE3u3QxxSux… Thanks to all the authors for their insightful contributions and our editor for their kind invitation and guidance.

Job Alert! Our lab is recruiting a Postdoctoral fellow to work on the interplay between mitochondrial morphology, mb contact sites, mtDNA dynamics and quality control. Have a look if interested! MRC MBU Cambridge University jobs.cam.ac.uk/job/46901/

It’s happening again! Mark your calendar 10 - 13 Jun 2025 and join us for the 2nd The ageing genome: from mechanisms to disease symposium embl.org/about/info/cou… via EMBL

Congrats to Chris Mutti on publishing his PhD research on mitoribosome assembly! This builds upon Lindsey Van Haute's work on the methyltransferase METTL15, revealing that its catalytic activity is not essential for mtSSU biogenesis. tandfonline.com/doi/full/10.10… MRC MBU Postdocs MRC MBU

Congratulations Mia!!! Maria Falkenberg elected to the European Molecular Biology Organization | University of Gothenburg gu.se/en/news/maria-…

New paper from us on the in vivo role of the LRPPRC/SLIRP protein complex and its crucial role in mammalian mtDNA gene expression: academic.oup.com/nar/advance-ar… Congratulations Diana Rubalcava for great work! Thank you to all coauthors for a very nice collaboration.

Hello everyone, the new season of MITOtalks is ready to roll, and we have some awesome MITOscience waiting.

This will be agreat meeting. Looking forward to attend!

Excited to speak at Cell Symposia #CSMito2024 in Sitges, Spain this October! Join us 👉 hubs.li/Q02Nj92K0

Sebastian Valenzuela presenting his project on one of our favorite proteins. Thanks everyone for a super 7th DNA polymerase meeting in Warsaw!