Madelynn Whittaker
@mn_whittaker
Just here for the CRISPR craic ✂️ 🧬 Currently, PhD Student @pennbioeng in the Musunuru Lab || @NSF Graduate Research Fellow || @ArtisVentures Fellow
ID: 1242508312559509510
https://www.linkedin.com/in/madelynn-whittaker-a5842b103/ 24-03-2020 17:47:29
85 Tweet
382 Followers
240 Following
I throughly enjoyed presenting my recent graduate work at the Cardiac Regeneration & Vascular Biology Conference in Venice of TU München and Universität München! 🇮🇹 What a beautiful venue to hear more about cutting edge cardiovascular science🫀🧬
Introducing CHARM: a new epigenome editor to methylate DNA at the promoter of a targeted gene. Our lab's collaboration with Jonathan Weissman's Lab's Edwin Neumann & Tessa Bertozzi shows deep silencing of brain PrP Paper: science.org/doi/10.1126/sc… Blog: cureffi.org/2024/06/27/int…
What if there was a (epi-)genetic editor that could find the prion virus throughout the brain and durably silence it? There is now, in mice. With implications well beyond prion diseases science.org/doi/10.1126/sc… science.org/doi/10.1126/sc… Jonathan Weissman's Lab Eric Vallabh Minikel Whitehead Institute MIT Dept of BE
We believe this will forge a path to a much-needed prion disease treatment, and we think CHARM could potentially be applied to other neurodegenerative diseases. Please also check out this excellent perspective piece by Madelynn Whittaker and Kiran Musunuru! science.org/doi/10.1126/sc…