Here's my talk at the 1st 🏳️‍🌈LGBTQI+ @ISCB Symposium, which was held on Monday online. It's about how coming out intersected with my education and scientific career. It's quite personal so if that's not your thing, skip it. Other talks on the ISCB channel. youtube.com/watch?v=AptW3K…

Another reminder to reach out to me or Ben Myers Lab if you work in the field of cell biology and/or cancer and want to visit SLC to share your work! Flight, accommodations, and fun times are fully covered by us!

Check it out! Also from the incomparable Ben Myers Lab and Keren Hilgendorf.

Today in Science Magazine we report how lipids specialize for life under the crushing pressures of the deep sea and what this means more broadly for the composition of cell membranes (1/n) science.org/doi/10.1126/sc…

Years ago Martin Rasmussen was on a Fulbright studying meningeal afferents in my lab & noticed dyes placed in CSF accumulate in trigeminal ganglia. This observation nucleated his PhD project in NedergaardLab & has now led to a new model of migraine pain. science.org/doi/10.1126/sc…

My lab has multiple openings for those interested in doing some very cool science in beautiful Colorado! Research assistants (tech/lab manager level): cu.taleo.net/careersection/… Postdoctoral fellows: cu.taleo.net/careersection/… DM or email me if interested and 🙏 share broadly 🪃

A fascinating discovery from Holly Ingraham on how nervous system can regulate bone growth...

Our paper on how FAM122A inhibits PP2A-B55alpha phosphatase complex is out in Nature Communications after 15 months. *First* structural model & extensive validation of how same helical motif in substrates and FAM122A bind to B55alpha (beat cryo-EM by 7 months). Extensive biology as well.

Finding your niche, exploring a new passion, and more insightful advice in this week’s DrGPCR Podcast Replay with @Myers_Lab. Listen to this episode again and learn more about Capseicin, Ion channels, Smoothened, and Class F GPCRs. ▶️bit.ly/3S7vIwm #gpcr #drgpcr

Prof John Tesmer of Purdue Biological Sciences has unveiled insights into the mechanisms that enable cell movement, discoveries that could pave the way for new treatments for cancer & inflammatory diseases. #Purdue #PurdueScience #Science #PurdueBiology #Biology bit.ly/3WtFE5T

Come see Justin English’s talk if you are around! He is doing awesome work at the intersection of syn bio, gpcr pharmacology, and genomics!

Finally: here is Sandeep, Jennifer, Sheng, and Sendi's paper on the autoinhibited state of P-Rex1 and the dynamic changes it undergoes as it binds PIP3. Quite the odyssey! Congrats! Jennifer Cash Sandeep Ravala GutkindLab doi.org/10.7554/eLife.… eLife - the journal

Please check out the results of the study (tinyurl.com/yp76aye9) of AT1R phosporylation and how it impacts arrestin and G-prot recruitment. We were priveleged to include a small bioinformatic contribution from our side. Additionally, results made it on the cover:)

#Hedgehog (Hh) signaling: Ben Myers Lab shows that GPCR kinase 2 (GRK2) activates SMO in #PrimaryCilia, allowing its binding to PKA-C and Hh pathway activation in various cellular & in vivo models #PLOSBiology plos.io/3AGYGgk

We're excited to announce the upcoming Postdoctoral Rising Stars Symposium University of Utah Health with 20 outstanding scientists from broad backgrounds and keynote by Elizabeth Villa, with generous support by Burroughs Wellcome Fund. Hosts U of Utah Dept of Biochemistry U of U NUIP U of Utah Department of Neurobiology University of Utah College of Pharmacy Huntsman Cancer Institute

Mark your calendars for this year's U of U Postdoc Rising Stars symposium! Excited to co-chair the Cell Biology and Cancer session with Minna Roh-Johnson.