🎼Félicitations, Prof Nidaa Abou Mrad pour votre nomination à la "Chaire de Professeur Senior en musicologie, neuropsychologie de la musique et neuromusicothérapie" à Sorbonne Université! Merci de porter haut le flambeau de la recherche libanaise 🇱🇧 icibeyrouth.com/culture/375561

☝️H.pylory aggravates RA, but how?🤔 This study shows that H. pylory: 🔸stabilises hypoxia-inducible factor 1α -->PAD4 ⬆️ 🔸ACPA⬆️-->synovial cell proliferation and inflammation⬆️ 🔸PAD4-mediated K1 citrullination--> Cit-K1⬆️--> anti-Cit-K1 antibody ⬆️ ard.bmj.com/content/early/…

Submit your abstract to the LSR ⭐️ Levant #Rheumatology meeting today and be part of the conversation! 👉To submit a poster: docs.google.com/forms/d/e/1FAI… 👉To register: conference.infomedweb.com/the-lebanese-s… #Beirut #Meeting #Education

👍examination of plasma proteins in giant cell arteritis! ✔️537 proteins different between active GCA and controls ✔️781 between inactive GCA and controls ✔️16 proteins associated with disease activity ❌limited use to distinguish active and inactive☹️ ard.bmj.com/content/early/…

☝️ Sequential lymph node biopsies after #CD19-CAR T-cell therapy: 🔹CD19+, CD20+ cells, follicular DC completely depleted after CD19-CAR T-cells, but not after #rituximab 🔹Follicular structures disrupted 🔹Plasma cells, T cells and macrophages unchanged ard.bmj.com/content/early/…

#Osteoporosis awareness campaign at Hotel Dieu #Beirut USJ #rheumatology department #Motivated #fellows

#Osteoporosis awareness campaign at Hotel Dieu #Beirut USJ #rheumatology department #Motivated #fellows 👩🏻‍⚕️👩🏻‍⚕️👩🏻‍⚕️

Efficacy & safety of sequential therapy with SC #belimumab & one cycle rituximab in #SLE 🔷 Ph3 RCT BLISS-BELIEVE study 🔷 BEL/PBO vs BEL/RTX 🔷 263 pts 🔷 SLEDAI-2K 👉 16.7% vs 19.4% achieved disease control (OR 1.27; p=0.5342) at wk 52 🔗 bit.ly/3yIp21e

FOREMOST is the first RCT designed for early oligoarticular PsA 🔎 308 pts randomised: apremilast 203; PBO 105 🔷 Mean (SD) PsA duration 9.9 (10.2) months 🔷 Primary endpoint: MDA sentinel joints at week 16 👉 Apremilast 33.9% vs PBO 16.0%, p=0.0008  🔗 bit.ly/3yVOUqk

Positive feedback loop PU.1-IL9 in Th9 promotes rheumatoid arthritis development 🔷 Study in PU.1-T cell-conditional knockout (KO) mice, IL-9 KO and IL-9R KO mice 👉 Targeting this signalling axis presents a potential target approach for treating RA 🔗 bit.ly/4cGJDk7

Safety & efficacy of #tofacitinib in juvenile idiopathic arthritis 🔴 Preliminary results of open-label, long-term extension study 🔷225 patients 🔺10 serious infections 🔺3 herpes zoster 🔺2 uveitis 🔷JIA-ACR70/90 response 60.0% & 33.6% at month 1 🔗 bit.ly/4dF0iWz

Higher RA disease activity associated with accelerated eGFR decline 🔷 Data from a large prospective registry study 🔷 31129 patients (median age: 58.0 years) ⬆️ Adjusted HRs for CKD stage G3a/b in low, moderate & high disease activity vs remission 🔗 bit.ly/3X26GjF

Low uveitis rates in patients with axial spondyloarthritis treated with #bimekizumab 🔎 Pooled results phase 2b/3 trials BE MOBILE 1 & 2 🔴 0.6% (2/349) of patients receiving BKZ experienced uveitis vs 4.6% (11/237) PBO (p=0.001) ❓ Protective effect? 🔗 bit.ly/3AD6xMf

Relationship between serum urate and changes in DECT monosodium urate crystal volume over 1 year in #gout 🔎 Individual participant data analysis 💠 MSU crystal dissolution (DECT) ↔️ SU <0.29 mmol/L 💠 MSU crystal formation ↔️ SU ≥0.48 mmol/L 🔗 bit.ly/3X4SaYo

Serum from patients with idiopathic inflammatory myopathy induces skeletal muscle weakness 🔎 Humanised ex vivo experimental platform 🐭 Muscles from healthy mice exposed to sera from 8 IIM pts ▶️ Force production ⬇️ across stimulation frequencies 🔗 bit.ly/3TcltY9

Interested in renal function in #rheumatoid #arthritis? Check out our latest publication from a large registry 🇺🇸 ▶️high disease activity linked to accelerated glomerular filtration over time ▶️disease activity linked to CKD onset (G3 stage) 🔗 ard.bmj.com/content/early/…

📢 Poster Session A 🌟 New data related to the ASAS Health Index is presented in Poster Session A 👉 spa-congress.org #Spondyloarthritis #Rheumatology #ASAS #ASASHi

✅ Studies suggest that social determinants of #health account for up to 50% of health outcomes!!! It is therefore KEY to understand the sources of #inequities in #lupus care! I have listed what I found when reviewing papers ➡️ Can YOU 👀 think of other determinants?

The Lebanese Society of Rheumatology Board representatives met with H.E. Minister of Health Dr Firass Abiad to discuss upcoming groundbreaking Society projects! Looking forward to advancing our shared goals for better patient care and research! Nadeen Hilal @kamelmroue

Busy discussions at the poster session 2/4 at the #Ghent International Congress #Spondyloarthritides