🧲 ᗑ The most interesting multiplet I’ve seen recently. This one particular Proton at 2.41 ppm has 5 different couplings: ³J to Fluorine, geminal ²J, 2*³J and ⁴J to the protons of the cyclobutane ring. #nmr #nmrchat #chemistry #organicchemistry

. Nature Communications (open) Overhauser enhanced liquid state NMR in one and two dimensions, corresponding Marina Bennati MPI for Multidisciplinary Sciences nature.com/articles/s4146… #NMRchat #NMR #DNPNMR 🧲

The effect of dissolved oxygen on the T1 relaxation times of NMR signals u-of-o-nmr-facility.blogspot.com/2008/09/effect… #nmrchat

Beautiful small Stellane - a fascinating and unique compound synthesized by the expert chemists at Enamine Ltd 🇺🇦 . These compounds are known to be benzene bioisosteres. Find out more in Enamine’s latest research: DOI: 10.1021/acs.orglett.4c01645 #nmrchat #drugdiscovery

The answer to the previous challenge. This one turned out to be easy 🙂 #nmr #nmrchat #Chemistry #organicchemistry #nmrchallenge

Spiro containing systems have greater three-dimensionality than flat aromatic comp. and in combination with the incorporation of one or more fluorine atoms can lead to promising results for biological and pharmacological activity of target molecule. #nmr #nmrchat #drugdiscovery

The same compound in different solvents. Notice that the most shielded CH₂ group is fully resolved only in D₂O 👌. Which spectrum do you prefer? #nmr #nmrchat #Chemistry #drugdiscovery

A piece of useful information on ¹H NMR of exchangeable protons (any protons that exist in a state of dynamic equilibrium with any free water). #nmr #nmrchat #chemistry #organicchemistry #spectroscopy

🧲 ᗑ Multiplet of the week. This one particular Proton has 5 different couplings: trans ³J to Fluorine, geminal ²J, trans ³J and two cis ³Js to the neighbouring protons. #nmr #nmrchat #chemistry #organicchemistry #spectroscopy

#NMRcredi C'est assez simple de distinguer la version original de la version sans sucres du Coca-Cola par RMN du proton. 😁 Si vous zoomez sur la ligne de base, vous allez distinguer les pics vous indiquant que ce n'est pas que de l'eau.

🍌 ¹H NMR Spectroscopy of Banana! Ever wondered what’s inside a banana at the molecular level? We have acquired the 1H NMR spectrum of a water banana extract in DMSO-d6. #nmr #nmrchat #chemistry #organicchemistry

The -SF₅ group has an ‘umbrella’ geometry, and the sulfur atom in the -SF₅ group is in an octahedral coordination environment. The pres. of an aliph group makes the fluorines at the edges and the fluorine at the vertex of the octahedron inequivalent. #nmr #nmrchat #chemistry

🧲☀️Cinnamic acid derivatives are a good example of why it is necessary to protect your NMR samples from direct sunlight. ℹ️These NMR spectra illustrate the transformation of the E-isomer into the Z-isomer when the sample is exposed to open light. #nmr #nmrchat #chemistry #uv

🙂 Recently, I encountered similar NMR problem in practice. ℹ️ Found the answer in Breitmaier’s book. ☝️Geminal couplings ²J(NH) distinguish the relative configurations of aldoximes/aldimines very clearly. #nmr #nmrchat #chemistry #organicchemistry #spectroscopy

ℹ️ In 1D TOCSY, a single peak is selected, and the signal is transferred from it to all J-coupled protons in a stepwise process. ❗️This technique can be particularly useful for separating spectra in mixtures of compounds. • #nmr #nmrchat #organicchemistry